Resistin, an Adipokine with Potent Proinflammatory Properties1

By M. Bokarewa, I. Nagaev, L. Dahlberg, U. Smith, A. Tarkowski. Journal of Immunology, 2005

1,025 citations recorded by the source corpus.

Subfields: Epidemiology, Physiology, Rehabilitation

View Paper: https://www.semanticscholar.org/paper/52e112ca1ee8726807ddbc0fd4286a586505c68a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Herbert Tilg
2. A. Moschen
3. K. Walsh
4. N. Ouchi
5. A. Tedgui
6. Z. Mallat
7. H. Kwon
8. J. Pessin

In Physiology

1. Herbert Tilg
2. K. Walsh
3. N. Ouchi
4. A. Tedgui
5. Z. Mallat
6. H. Kwon
7. J. Pessin
8. A. Chait

Citations in the corpus

• Adipokines in inflammation and metabolic disease (2011, background): “The pro-inflammatory properties of resistin in human mononuclear cells are evident, as resistin promotes the expression of TNF and IL-6 by these cell”
• Adipocytokines: mediators linking adipose tissue, inflammation and immunity (2006, background): “Resistin strongly upregulates the expression of TNF and IL-6 by human PBMCs and induces arthritis after injection into the joints of healthy mic”
• Adipokines Mediate Inflammation and Insulin Resistance (2013, background): “Resistin stimulates human peripheral mononuclear cells to produce IL-6 and TNF-α through the NF-κB signaling pathway, and rosiglitazone a PPARγ agonist suppresses the resistin expression in adipose tissues resulting in the attenuation of inflammatory responses (Bokarewa et al., 2005).”
• Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease (2020, background): “Resistin can upregulate inflammatory cytokines such as TNFα and IL-6 in monocytes and macrophages in a nuclear factor kappa-B (NFκB)-dependent manner (118), and is positively associated with circulating inflammatory markers such as C-reactive protein (CRP) and TNFα (107).”
• Obesity in autoimmune diseases: not a passive bystander. (2014, background): “High synovial rates were most frequently correlated with joint damage [94, 105–107].”
• Cytokines in atherosclerosis: pathogenic and regulatory pathways. (2006, background): “TNF- , IL-6, and IL-1 in human PBMC (70).”
• Adipokines as emerging mediators of immune response and inflammation (2007, background): “Furthermore, LPS has been reported to induce resistin gene expression in primary human and murine macrophages via a cascade involving the secretion of pro-inflammatory cytokines, and in human peripheral blood mononuclear cells resistin seems both to induce and be induced by IL-6 and TNF (induction o”