Mediators and moderators of treatment effects in randomized clinical trials.

By PhD Helena Chmura Kraemer, PhD G. Terence Wilson, DM MPhil FRCPsych Christopher G. Fairburn, MD W. Stewart Agras. Archives of General Psychiatry, 2002

2,649 citations recorded by the source corpus.

Subfields: Clinical Psychology, Experimental and Cognitive Psychology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/51a2902667101258791f5442cfd5681174c09368

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Clinical Psychology

1. Judea Pearl
2. Andrew F. Hayes
3. P. Kendall
4. M. O. Wright
5. Warren Mansell
6. A. Masten
7. David P. MacKinnon
8. Kosuke Imai

In Experimental and Cognitive Psychology

1. Dustin Tingley
2. Kosuke Imai
3. E. Watkins
4. Warren Mansell
5. Kate Cavanagh
6. C. Strauss
7. Jenny Gu
8. R. Bond

In Pharmacology

1. E. Watkins
2. Susan A. Murphy
3. Amery Wu
4. A. Kazdin
5. Bruno D. Zumbo
6. J. Teasdale
7. Warren Mansell
8. Kai Sassenberg

Citations in the corpus

• Don't Forget Your Body: Mindfulness, Embodiment, and the Treatment of Depression (2012, background): “Consequently, research designs allowing formal mediation analyses (Kraemer et al. 2002) are needed to elucidate the role of”
• Introduction to SMART designs for the development of adaptive interventions: with application to weight loss research (2014, methodology): “Data analyses associated with the aim to develop a more deeply-tailored AI are akin to, but go beyond, standard moderator analysis [69–72].”
• Mediation analysis. (2019, methodology): “Researchers from many fields have stressed the importance of assessing mediation in treatment and prevention research (Baranowski et al. 1998; Donaldson 2001; Judd & Kenny 1981a,b; Kraemer et al. 2002; MacKinnon 1994; Shadish 1996; Weiss 1997).”
• Examining the Influence of Teacher Behavior and Classroom Context on the Behavioral and Academic Outcomes for Students With Emotional or Behavioral Disorders (2008, background): “Kraemer and colleagues point out that the identification of moderator variables can help practitioners determine for whom the treatment is most effective ( Kraemer, Wilson, Fairburn, & Agras, 2002 ).”
• The role of self-statements as a mediator in treatment for youth with anxiety disorders. (2007, positive): “The potential mediating role of self-statements in treatment outcome followed Baron and Kenny (1986) and the implications of this model for randomized controlled trials (Holmbeck, 2002; Kraemer et al., 2002).”
• Cognitive Behavioural Processes Across Psychological Disorders: A Transdiagnostic Approach To Research And Treatment (2004, background): “Such studies could be conducted within the context of large randomized controlled trials (e.g. Kraemer et al. 2002) but cross-sectional, longitudinal, and particularly experimental designs lend themselves to the efficient testing of hypotheses regarding the role of safety behaviour.”
• The Second Special Issue on Evidence-Based Psychosocial Treatments for Children and Adolescents: A 10-Year Update (2008, background): “Mediation and moderation constitute a topic that has garnered considerable attention in recent years (eg, Hinshaw, 2002 ; Holmbeck, 1997 ; Kraemer, Wilson, Fairburn, & Agras, 2002 ).”
• When moderation is mediated and mediation is moderated. (2005, background): “There is by now a very large literature on the important topics of mediation and moderation (e.g., Aiken & West, 1991; Baron & Kenny, 1986; James & Brett, 1984; Judd & Kenny, 1981; Kenny, Kashy, & Bolger, 1998; Kraemer, Wilson, Fairburn, & Agras, 2002; MacKinnon, Lockwood, Hoffman, West, & Sheets,”