Leptin regulation of the mesoaccumbens dopamine pathway.

By S. Fulton, P. Pissios, Ramon Pinol Manchon, L. Stiles, Lauren E. Frank, E. Pothos, E. Maratos-Flier, J. Flier. Neuron, 2006

641 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Nutrition and Dietetics, Physiology

View Paper: https://www.semanticscholar.org/paper/515442355c0ed925768dfff32b8537d6823f4665

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In Endocrine and Autonomic Systems

In Nutrition and Dietetics

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Citations in the corpus

The mammalian circadian timing system: organization and coordination of central and peripheral clocks. (2010, background): “Cocaine and other drugs of abuse such as methamphetamine (see below) influence the reward HB VTA NAc Ret”
Reward, dopamine and the control of food intake: implications for obesity (2010, positive): “Preclinical and clinical studies have provided evidence of decreases in DA signaling in striatal regions [decreases in DAD2 (D2R) receptors and in DA release], that are linked with reward (NAc) but also with habits and routines (dorsal striatum) in obesity [56–58].”
‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders (2009, background): “Control signals go back and forth between mesocorticolimbic reward systems and hypothalamic regulation systems [45,126,133,147,156–164].”
The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. (2010, positive): “Great progress has been made in recent years toward understanding neural interactions between mesocorticolimbic reward systems and hypothalamic regulation systems of caloric hunger and satiety (Baldo and Kelley, 2007; Baldo et al., 2004; Berthoud and Morrison, 2008; Carr, 2007; Finlayson et al., 200”
Mechanisms of leptin action and leptin resistance. (2008, background): “Although ARC LRb neurons do not project to the VTA and there is little evidence for the modulation of the mesolimbic circuitry by NPY or melanocortin action, a number of research groups have demonstrated the presence of LRb-expressing VTA DA neurons and proven the ability of leptin to alter the phys”
Pathophysiology of Migraine: A Disorder of Sensory Processing. (2017, background): “The VTA is implicated in modulating food craving behaviors (600), as well as the drive to access highly palatable foods (3, 4), and increased leptin signaling in the VTA decreases food intake and firing rates of DA neurons (287, 414).”
Food reward in the absence of taste receptor signaling. (2008, positive): “We thus reason that the putative role of dopamine transmission in overeating and obesity might not be restricted to oral hedonics; rather, dopamine signaling could influence behavior also by coding for the food’s nutritive value (Figlewicz, 2003; Fulton et al., 2006; Hommel et al., 2006; Palmiter,”
Reward Mechanisms in Obesity: New Insights and Future Directions (2011, background): “In addition, ob/ob mice had reduced evoked dopamine release into the NAc (Fulton et al., 2006) and decreased somatodendritic vesicular stores of dopamine in VTA and SN (Roseberry et al.”