‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders

By Kent C. Berridge. Physiology and Behavior, 2009

1,085 citations recorded by the source corpus.

What brain reward systems mediate motivational ‘wanting’ and hedonic ‘liking’ for food rewards? And what roles do those systems play in eating disorders? This article surveys recent findings regarding brain mechanisms of hedonic ‘liking’, such as the existence of cubic-millimeter hedonic hotspots in nucleus accumbens and ventral pallidum for opioid amplification of sensory pleasure. It also considers brain ‘wanting’ or incentive salience systems important to appetite, such as mesolimbic dopamine systems and opioid motivation circuits that extend beyond the hedonic hotspots. Finally, it considers some potential ways in which ‘wanting’ and ‘liking’ might relate to eating disorders.

Subfields: Clinical Psychology, Endocrine and Autonomic Systems, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/cfe262872cfb2e9892ca003f882630c20019a2a3

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Citations in the corpus

Who is The Fairest One of All? How Evolution Guides Peer and Media Influences on Female Body Dissatisfaction (2011, background): “…nd ed so le ly fo r t he p er so na l u se o f t he in di vi du al u se r a nd is n ot to b e di ss em in at ed b ro ad ly . certainly not limited to, the endogenous opioid and endocannabinoid systems, and the mesolimbic dopaminergic system (Berridge, 2009; Kaye, 2010; Kaye, Fudge, & Paulus, 2009).”
Reward, dopamine and the control of food intake: implications for obesity (2010, positive): “The hedonic (‘liking’) properties of food appear to depend on, among others, opioid, cannabinoid and GABA neurotransmission [36].”
The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. (2010, positive): “Similar aversion is produced by even temporary inhibition of neurons in roughly the same hotspot (via microinjection of GABA agonist muscimol) (Ho and Berridge, 2009; Shimura et al., 2006).”
Reward Mechanisms in Obesity: New Insights and Future Directions (2011, background): “…accumbens and dorsal striatum, which receive dopaminergic input from the ventral tegmental area and substantia nigra, regulate the motivational and incentive properties of food (Baicy et al., 2007; Berridge, 1996, 2009; Farooqi et al., 2007; Malik et al., 2008; Söderpalm and Berridge, 2000).”
RETHINKING THE EMOTIONAL BRAIN (2012, neutral): “…1980; Balleine and Killcross, 1994; Killcross and Robbins, 1993; Everitt et al., 1999; Cardinal et al., 2002; Ikemoto and Panksepp, 1999; Parkinson et al., 1999; Koob, 2009; Sesack and Grace, 2010; Berridge, 2007, 2009; Berridge and Robinson, 1998; Hyman et al., 2006; Nestler, 2004; Kelley, 2004).”