Neural induction, the default model and embryonic stem cells

By I. Muñoz-Sanjuán, Ali H. Brivanlou. Nature Reviews Neuroscience, 2002

654 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/509cd96b582487012d6c75673a8c806de87b479f

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In Molecular Biology

1. G. Keller
2. Qi-Long Ying
3. Austin G Smith
4. Hynek Wichterle
5. J. A. Porter
6. I. Lieberam
7. Tom Misteli
8. M. Li

Citations in the corpus

• Directed differentiation of telencephalic precursors from embryonic stem cells (2005, result): “Autonomous neural differentiation in the absence of exogenous inhibitory factors could be consistent with the so-called 'neural default' mode”
• Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture (2003, background): “Studies in Xenopus laevis and chick embryos have given rise both to a permissive, or default, mode”
• Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling (2009, background): “, and promoting neuralization of primitive ectoderm by BMP inhibitio”
• Directed differentiation of embryonic stem cells into motor neurons. (2002, background): “In vivo, neural induction appears to depend on the blockade BMP signaling (Munoz-Sanjuan and Brivanlou, 2002) and exposure to FGFs (Streit et al.”
• REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. (2005, background): “Nervous system development relies on a network of transcriptional repressors and activators that control the orderly acquisition and maintenance of neuronal traits (reviewed in Anderson and Jan [1997], Edlund and Jessell [1999], Munoz-Sanjuan and Brivanlou [2002] , and Sasai [1998]).”
• TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells (2005, background): “…a prominent role for TGFβ signaling in the earliest cell fate decisions of embryogenesis, including neural induction and mesendoderm specification in Xenopus (reviewed by Munoz-Sanjuan and Brivanlou, 2002), and primitive streak and mesoderm formation in the mouse (reviewed by Goumans et al., 2000).”
• Neural Bases of Cognitive Development (2007, background): “A class of chemical agents referred to as transforming growth factors is responsible for the subsequent transformation of this undifferentiated tissue into nervous system tissue (Murloz-Sanjuan & Brivanfou, 2002).”
• Chromatin in pluripotent embryonic stem cells and differentiation (2006, background): “It is possible that clonal selection is not entirely random, as there is evidence that ES cells enter the neuronal lineage by defaul”
• Dorsal-ventral patterning and neural induction in Xenopus embryos. (2004, background): “Xenopus ectoderm is relatively resistant to neuralization, but neural differentiation can be elicited by cell dissociation and culture for several hours (reviewed by Weinstein & Hemmati- Brivanlou 1999, Munoz-Sanjuan & Brivanlou 2002).”