Regulatory T cells and infection: a dangerous necessity

By Y. Belkaid. Nature reviews. Immunology, 2007

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Mechanisms of foxp3+ T regulatory cell-mediated suppression. (2009, background): “However, multiple studies in vivo have shown that secretion of IL-10 by Treg cells constitutes an important component of their suppressive effects (Belkaid, 2007; McGeachy et al., 2005).”
Molecular Mechanisms of Treg-Mediated T Cell Suppression (2012, background): “The importance of IL-10 in Treg function in vivo has been extended to infection and EAE models (McGeachy and Anderton, 2005; Belkaid, 2007).”
How regulatory T cells work (2008, background): “, they also block beneficial responses by preventing sterilizing immunity to certain pathogen”
Vitamin effects on the immune system: vitamins A and D take centre stage (2008, background): “Although transforming growth factor-β (TGFβ) drives the generation of induced T Reg cells in peripheral tissue”
Phenotypic and functional specialization of FOXP3+ regulatory T cells (2011, background): “In addition to preventing autoimmunity, T Reg cells regulate immunity to infections of viral, bacterial or parasitic origin, and can also restrain immune responses directed towards tumours or transplanted tissu”