Peroxisomes and oxidative stress.

By M. Schrader, H. Fahimi. Biochimica et Biophysica Acta, 2006

810 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/4d6d4b9d0e491bebea45bd7a213663c10fd4fc92

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

Significance of Antioxidant Potential of Plants and its Relevance to Therapeutic Applications (2015, background): “However, it is also important to consider that free radicals are not harmful at all times; rather, their toxicity depends on several factors including type of ROS/RNS, their concentration and localization, and the kinetics of production and elimination [70].”
Redox compartmentalization in eukaryotic cells. (2008, background): “ROS generating enzymes include acyl-CoA oxidase, urate oxidase, xanthine oxidase, D-amino acid oxidase, pipecolic acid oxidase, Daspartate oxidase, sarcosine oxidase, glycolate oxidase, hydroxyacid oxidase 2 and 3, and polyamine oxidase [178,179].”
Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies (2017, background): “CAT is mainly located in peroxisomes and catalyzes the reduction of H2O2 into H2O and O2 [49].”
Antioxidant response mechanism of freshwater microalgae species to reactive oxygen species production: a mini review (2020, background): “The site for O2 - in peroxisome is identified to be in the organelle matrix and peroxisome membrane [42].”
Oxidative Stress and Oxidative Damage in Carcinogenesis (2010, background): “In rat liver, peroxisomes produce approxi- mately 35% of all H2O2 from normal oxygen consumption (Schrader and Fahimi 2006).”
The Role of Oxidative Stress in Neurodegenerative Diseases (2015, background): “Peroxisomes are present in most eukaryotic cells and participate in multiple metabolic pathways including fatty acid oxidation, phospholipid biosynthesis, amino acid catabolism, and oxidative part of the pentose phosphate pathway [10, 39].”
Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. (2014, background): “13) and is found mainly in peroxisomes (261).”
Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment (2009, positive): “Besides the mETC, low levels of ROS are produced by membrane-localized NADPH oxidase (Nox) enzymes (65), peroxisomes (100), and the cytochrome p450 system (43).”
Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling (2018, neutral): “Catalase is normally found at high concentrations in peroxisomes, where H2O2 is mainly produced by the β oxidation of fatty acids and might have no signaling role (Schrader and Fahimi, 2006).”