Rates of Behavior and Aging Specified by Mitochondrial Function During Development

By A. Dillin, A. Hsu, N. Arantes-Oliveira, J. Lehrer-Graiwer, H. Hsin, Andrew G. Fraser, R. Kamath, J. Ahringer, C. Kenyon. Science, 2002

1,069 citations recorded by the source corpus.

Subfields: Aging, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/4c184c1af071c0adafc739ac1377d7e59c05bb69

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aging

1. C. Kenyon
2. A. Dillin
3. Ronald H. A. Plasterk
4. J. Ahringer
5. F. Simmer
6. R. Kamath
7. Suzanne C Wolff
8. Jenni Durieux

In Molecular Biology

1. C. Kenyon
2. M. Brand
3. A. Dillin
4. J. Ahringer
5. R. Kamath
6. Toren Finkel
7. Andrew G. Fraser
8. Nataliya Libina

In Physiology

1. M. Brand
2. Luis A. Rajman
3. A. Dillin
4. M. Hansen
5. D. Sinclair
6. C. Kenyon
7. C. Palmeira
8. Nicholas A. Bishop

Citations in the corpus

• The Cell Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity (2011, positive): “RNAi of cco-1 slows development, growth, movement and reduces fecundity (Dillin et al., 2002b).”
• Trends in oxidative aging theories. (2007, background): “Even treatment with the Complex III inhibitor, antimycin A (which is extremely toxic to mammals), also extends life span [81].”
• Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions (2003, methodology): “elegans using this RNAi library or other techniques (Gönczy et al. 2000; Maeda et al. 2001; Dillin et al. 2002; Piano et al. 2002; Ashrafi et al. 2003; Lee et al. 2003; Pothof et al. 2003).”
• Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans (2007, background): “Inhibiting respiration also extends lifespan in C. elegans (Feng et al., 2001; Dillin et al., 2002; Lee et al., 2003).”
• The sites and topology of mitochondrial superoxide production (2010, background): “elegans (Dillin et al., 2002; Lee et al., 2003).”
• The plasticity of aging: insights from long-lived mutants. (2005, background): “Treating worms with daf-2 RNAi from the time of hatching extends life span and delays reproduction, but treating them as young adults extends life span to the same extent with little or no effect on reproduction (Dillin et al., 2002a).”
• Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. (2008, neutral): “…signaling (IIS) (Friedman and Johnson, 1988; Gottlieb and Ruvkun, 1994; Kenyon et al., 1993; Larsen, 1993), caloric intake (Houthoofd et al., 2002), mitochondrial respiration (Dillin et al., 2002; Lakowski and Hekimi, 1996; Lee et al., 2003), and germline function (Arantes-Oliveira et al., 2002).”
• Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging (2013, background): “HIF-1a modulation may have differential effects on lifespan depending on the animal’s diet or whether the mtUPR is activated (Dillin et al., 2002; Durieux et al., 2011; Houtkooper et al., 2013).”