The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4

By Assen Roguev, Daniel Schaft, A. Shevchenko, W. Pijnappel, M. Wilm, R. Aasland, A. Stewart. EMBO Journal, 2001

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Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (2006, background): “Primers are the same as in Figure 3B. (E) Transcription assay performed as in Figure 2B. (F) In vivo ChIP on the RARb2 promoter in P19 cells using anti-H3K4me3 and anti-H3K4me2 antibodies as a function of RNF20/40 depletion by RNAi. a subunit of the SET1 and the MLL families of HKMTases (Roguev et a”
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. (2004, background): “…homolog of DPY-30,Methyltransferase Complex In addition to RNA polymerase II, discussed below, ho- Sdc1 (Miller et al., 2001; Nagy et al., 2002; Roguev et al., 2001).mologs of the other proteins in the menin complex are found in the yeast histone methyltransferase (HMTase) The menin-associated…”
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. (2003, background): “Thus, Set1 is generally targeted to active Pol II- DNA binding repressor (Kadosh and Struhl, 1998; Rund- lett et al., 1998).”
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast (2002, background): “) Because expression levels of SET1 and its associated gene”