Opinion: Lipid droplets: a unified view of a dynamic organelle

By Sally Martin, Robert G. Parton. Nature reviews. Molecular cell biology, 2006

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The lipid droplet is an important organelle for hepatitis C virus production (2007, background): “It dynamically moves through the cytoplasm, interacting with other organelles, including the endoplasmic reticulum (ER”
Cellular cholesterol trafficking and compartmentalization (2008, background): “Lipid droplets were previously considered to be passive fat deposits but are now emerging as dynamic, regulated organelle”
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores (2009, background): “Lipid droplets and lipid droplet proteins have been the subject of multiple recent reviews [8–14], including many articles within this issue.”
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. (2013, background): “Based on the tight association of LDs with the ER and the ER localization of enzymes involved in synthesizing neutral lipids for LDs, a prominent model posits that LDs form by growing a lipid lens in the ER that subsequently buds off into the cytoplasm (Martin and Parton, 2006).”
Dengue virus induced autophagy regulates lipid metabolism (2010, background): “, 2009), which are cellular stores of triglycerides (TGs) and cholesterol esters (Martin and Parton, 2006).”