IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation1

By M. Kurowska-Stolarska, B. Stolarski, P. Kewin, G. Murphy, C. Corrigan, S. Ying, N. Pitman, A. Mirchandani, Batika M. J. Rana, N. Van Rooijen and 5 more. Journal of Immunology, 2009

729 citations recorded by the source corpus.

Subfields: Immunology, Surgery

View Paper: https://www.semanticscholar.org/paper/426c6c9a481f9b770c33291c5848d1d51cec6a77

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In Immunology

1. R. Locksley
2. S. Gordon
3. G. Harry
4. C. McPherson
5. Rubén Orihuela
6. F. Martínez
7. S. V. Van Dyken
8. A. Mantovani

In Surgery

1. S. Gordon
2. R. Locksley

Citations in the corpus

• Alternative activation of macrophages: mechanism and functions. (2010, background): “IL-33, a Th2 cell product, binds to ST2L, a subunit of the IL-33 receptor, to amplify Th2 cytokine production and AAM induction (Kurowska-Stolarska et al., 2009).”
• Microglial M1/M2 polarization and metabolic states (2016, background): “Other cytokines induce M2 polarization such as IL-3 (Kuroda et al., 2009), IL-21 (Pesce et al., 2006) and IL-33, (Kurowska-Stolarska et al., 2009) as well as the chemokines, CCL2 and CXCL4 (Roca et al., 2009; Gleissner et al., 2010).”
• INTERLEUKIN-4- AND INTERLEUKIN-13-MEDIATED ALTERNATIVELY ACTIVATED MACROPHAGES: ROLES IN HOMEOSTASIS AND DISEASE (2013, positive): “Accordingly, macrophage depletion or deficiency during type 2 inflammation induced by IL-33, chitin, or helminth infection results in reduced recruitment of eosinophils (25, 117, 118).”
• Macrophage plasticity, polarization, and function in health and disease (2018, background): “airways of patients with atopic dermatitis and asthma which correlated with disease severity (Kurowska-Stolarska et al., 2009).”