Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice

By Tiziano Barberi, P. Klivényi, N. Calingasan, Hyojin Lee, H. Kawamata, Kathleen Loonam, A. Perrier, J. Brusés, M. Rubio, N. Topf and 5 more. Nature Biotechnology, 2003

666 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4174932965e9eae5f152cd0cb10b8a4a0b706d57

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The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. G. Keller
2. Kenji Mizuseki
3. Hans Clevers

In Developmental Neuroscience

1. G. Keller
2. Kenneth R. Boheler
3. A. Wobus

In Molecular Biology

1. G. Keller
2. Kenneth R. Boheler
3. A. Bishop
4. Gregory J. Hannon
5. A. Wobus
6. H. Rippon
7. V. Narry Kim
8. Phillip D. Zamore

Citations in the corpus

• Specification of motoneurons from human embryonic stem cells (2005, background): “, with subsequent differentiation into large projection neurons, such as midbrain dopaminergic neurons and spinal motoneurons, in response to specific sets of morphogen”
• Embryonic stem cells (2004, background): “form synapses and can generate action potentials), integrate into the brain and, in at least one case, have corrected the phenotype of a neurodegenerative disease (Barberi et al. 2003; Benninger et al. 2003; Chiba et al. 2003).”
• Embryonic stem cells: prospects for developmental biology and cell therapy. (2005, background): “(25) showed that transplantation of ntES cell-derived dopaminergic neurons could correct the phenotype of a mouse model of Parkinson’s disease.”
• Directed differentiation of telencephalic precursors from embryonic stem cells (2005, background): “This is the first quantitative report of such efficient in vitro induction of telencephalic precursors from ES cells (qualitative detection of Bf1 induction has also been reporte”
• Embryonic stem cell differentiation: emergence of a new era in biology and medicine. (2005, background): “Populations not overexpressing exogenous Nurr1 generated with the stromal cell coculture protocol have also been transplanted into Parkinsonian mice (Barberi et al. 2003).”
• A MicroRNA Feedback Circuit in Midbrain Dopamine Neurons (2007, background): “A number of studies have shown that ES cultures can generate cells with a mDN phenotype and that the developmental program in vitro appears to recapitulate the temporal course of normal mDN maturation ( Barberi et al. 2003; Kim et al. 2002; Martinat et al. 2006; Sonntag et al. 2004).”