Noninvasive imaging of quantum dots in mice.

By B. Ballou, B. Lagerholm, L. Ernst, M. Bruchez, A. Waggoner. Bioconjugate chemistry, 2004

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Biodegradable luminescent porous silicon nanoparticles for in vivo applications (2009, background): “, clinical translation has been impeded owing to concerns regarding the biodegradability of such material”
Review of health safety aspects of nanotechnologies in food production. (2009, background): “, size, surface charge, functionalizedgroups) are likely to influence the absorption, metabolism, distribution and excretion (ADME) (Ballou et al., 2004; des Rieux et al., 2006; Florence, 2005; Jani et al., 1990; Roszek et al., 2005; Singh et al., 2006) of NPs present in food.”
Effects of nanomaterial physicochemical properties on in vivo toxicity (2009, neutral): “toxicity; however, they found differences in accumulation and clearance [101].”
Clearance Properties of Nano-sized Particles and Molecules as Imaging Agents: Considerations and Caveats (2008, background): “Intravenously injected QDs have been shown to be detectable in the liver and kidney 28 days post-injection [34] and within the lymph nodes and bone marrow of mice 133 days after injection [35,36].”
Drug delivery and nanoparticles: Applications and hazards (2008, background): “For example quantum dots cores can be coated with hydrophilic polyethylene glycol (PEG) to increase the half life time (Ballou et al 2004).”