A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

By G. Dietzl, Doris Chen, F. Schnorrer, Kuan-Chung Su, Yu. V. Barinova, M. Fellner, Beate Gasser, Kaolin Kinsey, S. Oppel, Susanne Scheiblauer and 4 more. Nature, 2007

2,863 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/409e9d1762e19199fa6ec722f58863baba917a91

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Citations in the corpus

Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees (2013, methodology): “24826) was obtained from the Vienna Drosophila RNAi Center (VDRC) (55).”
Cell-type Specific Labeling of Synapses in vivo through Synaptic Tagging with Recombination (STaR) (2014, background): “The synaptic markers can be readily integrated into genetic schemes, such as RNA interference and mosaic analysis with a repressible cell marker (MARCM), to study the molecular mechanisms underlying synaptic specificity (Dietzl et al., 2007; Lee and Luo, 2001; Ni et al., 2009).”
Layered reward signaling through octopamine and dopamine in Drosophila (2012, neutral): “The uas-oamb RNAi [2861GD] and uas-oct β 2R RNAi [104524KK] were obtained from the VDRC 33 .”
Modelling learning and memory in Drosophila to understand Intellectual Disabilities. (2020, positive): “With these techniques, researchers have finely manipulated most of the genes in the Drosophila genome (Dietzl et al., 2007; Bellen et al., 2011; Bischof et al., 2012; Perkins et al., 2015).”
Spacing Effect: SHP2 Phosphatase Regulates Resting Intervals Between Learning Trials in Long-Term Memory Induction (2009, positive): “Second, we exposed these flies to a cold-shock treatment (2 min in ice water), to which ARM is resistant (Tully et al., 1994; DeZazzo and Tully, 1995 ), 2 hr after training and found that it abolished the massed training-elicited memory enhancement (Figure 3D).”
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. (2008, background): “A UAS-Dicer2 transgene was coexpressed with Sd RNAi transgenes to increase RNAi efficiency (Dietzl et al., 2007).”
Many roads to maturity: microRNA biogenesis pathways and their regulation (2009, background): “In addition, insights into the regulation of miRNA processing could be applied to enhance RNA”
The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing and Mosaic Analysis (2010, positive): “, 1998), including a UAS-RNAi library against most predicted genes in the Drosophila genome (Dietzl et al., 2007).”
Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery (2011, background): “They have created a collection of RNAi knockdown strains targeting 90% of the entire fly genome and have made it available to the research community (Dietzl et al., 2007).”
Short Neuropeptide F Acts as a Functional Neuromodulator for Olfactory Memory in Kenyon Cells of Drosophila Mushroom Bodies (2013, positive): “…of Drosophila melanogaster were used for crosses: OK107-GAL4 (IV) (Connolly et al., 1996), MB247-GAL4 (III) (Zars et al., 2000), UAS-dicer2 (II) (Dietzl et al., 2007), UAS-sNPF-RNAi (X;II) (Lee et al., 2004), UAS-sNPF-RNAi (X), MB247-GAL80 (II) (Krashes et al., 2007), elav-GAL4 (X) (Lin and…”
A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster (2015, methodology): “The following RNAi lines were obtained from the VDRC (Dietzl et al., 2007): VGAT-RNAi (X-stock #45917), VGAT-RNAi (II- stock #45916), Trh-RNAi (II-#105414), GABABR3-RNAI (III-#50176).”