Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

By A. Donovan, A. Brownlie, Yi Zhou, J. Shepard, S. J. Pratt, J. Moynihan, B. Paw, Anna Drejer, B. Barut, A. Zapata and 10 more. Nature, 2000

1,691 citations recorded by the source corpus.

Subfields: Genetics, Hematology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/3f2819fa761572ab5cdb59e4469c0b794e7293b9

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In Genetics

1. T. Ganz
2. Kostas Pantopoulos
3. C. Wood
4. C. Brauner
5. A. Farrell
6. D. Richardson
7. D. Kalinowski
8. G. Papanikolaou

In Hematology

1. T. Ganz
2. Leonard I. Zon
3. Kostas Pantopoulos
4. G. Papanikolaou
5. C. Wood
6. C. Brauner
7. A. Farrell
8. D. Richardson

In Nutrition and Dietetics

1. T. Ganz
2. C. Wood
3. C. Brauner
4. A. Farrell
5. C. Bridges
6. G. Papanikolaou
7. Kostas Pantopoulos
8. D. Templeton

Citations in the corpus

• Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway (2002, background): “As mentioned before, recent studies have shown that ferroportin 1/hephaestin and/or hephaestin-independent iron export systems might play a key role in ferrous iron transport across basal membrane of enterocytes in the gut (Vulpe et al., 1999; Donovan et al., 2000; Kaplan and Kushner, 2000).”
• Chemistry and biology of eukaryotic iron metabolism. (2001, background): “Its message contains an IRE in the 5 untranslated region that appears to mediate IRP binding and it is clear that transcript levels are modulated in response to iron and hypoxia [130,131].”
• The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer (2005, background): “Several proteins have been implicated in the trafficking and release of iron, including hephaestin (Vulpe et al., 1999) and ferroportin 1 (also known as metal transporter 1 or iron-regulated transporter 1; Abboud and Haile, 2000; Donovan et al., 2000; McKie et al., 2000).”
• Systemic iron homeostasis. (2013, background): “The sole known mammalian iron exporter is ferroportin [also called Scl40a1, iron-regulated gene 1 (IREG1), or metal transporter protein 1 (MTP1)] (1, 59, 151).”
• Homeostasis and toxicology of essential metals (2012, background): “The cellular Fe exporter ferroportin was simultaneously identified in the mouse and via positional cloning in anemic zebrafish (Abboud and Haile, 2000; Donovan et al., 2000; McKie et al., 2000).”
• Identification of an intestinal heme transporter. (2005, background): “…(Raffin et al., 1974), which then enters the low molecular weight pool of iron in the enterocyte, along with iron absorbed as inorganic (i.e., non-heme) iron, and exits the enterocyte via the basolateral transporter ferroportin (McKie et al., 2000; Donovan et al., 2000; Abboud and Haile, 2000).”
• Iron metabolism and toxicity. (2005, background): “Basolateral iron transport is mediated by ferroportin 1 (Donovan et al., 2000), also found in literature as IREG1 (McKie et al.”