The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer
By D. Kalinowski, D. Richardson. Pharmacological Reviews, 2005
690 citations recorded by the source corpus.
Subfields: Genetics, Hematology, Oncology
View Paper: https://www.semanticscholar.org/paper/f6d79219b31126a400ad66bbbabd16778d9eaf5d
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Citations in the corpus
- Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come (2016, background): “As iron is vital to cellular proliferation, cancer cells exhibit a higher level of surface transferrin receptors than normal cells (Richardson and Baker, 1990; Richardson and Baker, 1992; Trinder et al., 1996; Kalinowski and Richardson, 2005).”
- Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. (2008, background): “Indeed, investigators have explored this possibility by testing iron chelators for anticancer properties ( Kalinowski and Richardson, 2005 ).”