PHO2, MicroRNA399, and PHR1 Define a Phosphate-Signaling Pathway in Plants1[W][OA]

By Rajendra Bari, Bikram Datt Pant, Mark Stitt, W. Scheible. Plant Physiology, 2006

1,032 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/3cd301de93a1622b86c2537d1507c967a2b53608

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Plant Science

Citations in the corpus

Small RNAs as big players in plant abiotic stress responses and nutrient deprivation. (2007, background): “miR399 levels increase dramatically in Pi-deprived plants [29,30,32] but fall rapidly after the addition of Pi [32] .P i starvation strongly induces the expression of all six MIR399 genes and this is rapidly reversed by Pi addition [ 32 ].”
A Central Regulatory System Largely Controls Transcriptional Activation and Repression Responses to Phosphate Starvation in Arabidopsis (2010, background): “MiR399, IPS1 and PHF1 are all under the control of PHR1, which itself is sumoylated in vitro by SIZ1, further strengthening the central role of PHR1 in the control of Pi starvation responses [12,18,20,22].”
MicroRNA399 is a long-distance signal for the regulation of plant phosphate homeostasis (2008, methodology): “…induction of a subset of phosphate starvation-induced (PSI) genes, including some encoding phosphate transporters (Aung et al., 2006; Bari et al., 2006), and accumulate Pi to high levels (three- to fivefold increased) in shoots but not roots (Bari et al., 2006; Delhaize and Randall, 1995).”
Origin, biogenesis, and activity of plant microRNAs. (2009, positive): “In those studies where protein production was measured, a discrepancy was observed between the extent of miRNA-directed transcript degradation and the loss of protein accumulation (Aukerman and Sakai, 2003; Bari et al., 2006; Chen, 2003; Gandikota et al., 2007), suggesting that plant miRNAs may also”
Abiotic Stress Responses in Plants: Unraveling the Complexity of Genes and Networks to Survive (2013, background): “As for miR395, also the expression of miR399 is regulated by a transcription factor, the MYB TF PHOSPHATE STARVATION RESPONSIVE1 (PHR1; [109]).”
WRKY75 Transcription Factor Is a Modulator of Phosphate Acquisition and Root Development in Arabidopsis1[C][W][OA] (2007, background): “Among the known regulators, microRNA miR399, representing a class of noncoding small RNAs that generally function as posttranscriptional negative regulators, has been implicated in regulating Pi homeostasis (Bari et al., 2006; Chiou et al., 2006).”
Strategies for improving phosphorus acquisition efficiency of crop plants. (2010, background): “The 244 microRNA miR399 might be the mobile signal assuring coordinated responses to P 245 deficiency between shoot and root (Bari et al., 2006).”
Small RNAs and Their Roles in Plant Development (2009, background): “A Myb transcription factor, PHOSPHATE STARVATION RESPONSE 1 (PHR1), promotes the expression of MIR399 genes in response to Pi starvation (Bari et al. 2006).”
Stress Response Versus Stress Tolerance: A Transcriptome Analysis of Two Rice Lines Contrasting in Tolerance to Phosphorus Deficiency (2009, background): “…to inorganic phosphate starvation (Yi et al. 2005), the “phosphate-induced protein” (phi-1; Os02g52040), and the “phosphate starvation response” factors (PHR1, Os03g21240; PHR2, Os07g25710) that form a regulatory circuit with PHO2 (Os06g40500) and microRNA399 (Fang et al. 2008; Bari et al. 2006).”
Uncovering Small RNA-Mediated Responses to Phosphate Deficiency in Arabidopsis by Deep Sequencing1[W][OA] (2009, background): “…STARVATION RESPONSE1 (PHR1) MYB transcription factor, which activates a group of Pi starvation-induced genes, includingMIR399s (Rubio et al., 2001; Bari et al., 2006), we analyzed the existence of P1BS cis-element, the biding site of PHR1, within the 2-kb sequences upstream of miRNA hairpins.”
A MicroRNA Superfamily Regulates Nucleotide Binding Site–Leucine-Rich Repeats and Other mRNAs[W][OA] (2012, background): “In some instances, the miRNAs or their precursors may move through plasmodesmata and different stages in the feedback system occur in adjacent cells or in separate roots and shoots (Bari et al., 2006; Pant et al., 2008).”
Functional biology of plant phosphate uptake at root and mycorrhiza interfaces. (2007, background): “Subsequently, Aung et al. (2006) and Bari et al. (2006) showed that a mutation in a miR399 target gene is responsible for the Pi overaccumulator phenotype in the pho2 mutant (Delhaize & Randall, 1995).”