Transcriptional control of adipocyte formation.

By S. Farmer. Cell Metabolism, 2006

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How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Adipocytes as regulators of energy balance and glucose homeostasis (2006, background): “There have been several thorough reviews on this aspect of adipose biology recentl”
Developmental origin of fat: tracking obesity to its source. (2007, positive): “These stages are orchestrated by a transcriptional cascade involving the nuclear receptor PPARγ and members of the C/EBPs family (Farmer, 2006).”
Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications (2019, background): “All of these steps are controlled by a network of interacting transcription factors operating to coordinate the expression of many hundreds of proteins responsible for establishing the mature fat cell phenotype (Figure 2) [75,76].”
PPAR agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein (2012, positive): “First, PPARg functions as a master regulator of both white and brown adipocytes (reviewed in [Farmer, 2006]).”
TNF-α and adipocyte biology (2007, background): “The transcriptional regulation of adipocyte differentiation has been extensively studied, at least in vitro (for reviews see, [152,153]).”
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. (2013, neutral): “The advances in brown adipose cell biology during the last decade have increased our understanding of the cellular origin (27–29), function (8, 13, 29), and adult human tissue distribution (2, 3, 7, 9) of BAT.”