The cerebral signature for pain perception and its modulation.

By Irene Tracey, P. Mantyh. Neuron, 2007

1,791 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Pharmacology, Physiology

View Paper: https://www.semanticscholar.org/paper/19e08e0d50782ef5d26eb90375f92322e899c3fa

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Citations in the corpus

Pain and the brain: Specificity and plasticity of the brain in clinical chronic pain (2010, background): “A large number of studies have demonstrated a network of brain areas consistently activated with acute thermal, mechanical, and chemical painful stimuli [4,15,100,101,112].”
Functional imaging studies of emotion regulation: A synthetic review and evolving model of the cognitive control of emotion (2012, neutral): “While responses to painful stimuli have a strong negatively-valenced affective component, this component may itself have a distinct neural signature due to its recruitment of dedicated pain-specific neural pathways 136, 137 .”
A common neurobiology for pain and pleasure (2008, background): “This circuit, which consists of excitatory and inhibitory cells, communicates with neurons in the prefrontal cortex, the hypothalamus and the amygdala to control the nociceptive afferent pathway in the spinal and trigeminal dorsal hor”
Why fish do not feel pain (2016, background): “…regions (including prefrontal cortex, anterior cingulate cortex, somatosensory areas I [SI] and II [SII], and the insular cortex) that consistently becomes active during the experience of pain in humans (Schnitzler and Ploner, 2000; Tracey and Mantyh, 2007; Moayedi, 2014; Mano and Seymour, 2015).”
Models and mechanisms of hyperalgesia and allodynia. (2009, background): “Reorganization of sensory processing in cortical areas may also be long-lasting (138, 518, 519, 532).”
TFOS DEWS II pain and sensation report (2017, neutral): “Sensitized spinal dorsal horn neurons project to higher brain centers and are necessary to engage thalamocortical and limbic pathways that underlie the discriminative and affective aspects of pain [384].”
Insects have the capacity for subjective experience (2016, background): “There is a dynamic core of cortical regions (including prefrontal cortex, anterior cingulate cortex, somatosensory areas I [SI] and II [SII], and the insular cortex) that consistently becomes active during the experience of pain in humans (Schnitzler and Ploner, 2000; Tracey and Mantyh, 2007; Moayed”
The influence of negative emotions on pain: Behavioral effects and neural mechanisms (2009, neutral): “…anterior cingulate and insular cortices, amygdala, hypothalamus and brainstem structures like the periaqueductal grey (PAG), rostral ventromedial medulla, dorsolateral pons/ tegmentum, and the descending projections to the spinal dorsal horn (for an overview see Tracey and Mantyh, 2007).”