Role of neurotrophic factors in depression.

By Eero Castrén, V. Võikar, T. Rantamäki. Current opinion in pharmacology (Print), 2007

697 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/a93def85cf6b87e6cd0e2738b59093e49da80b81

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. L. Monteggia
2. T. Rantamäki
3. H. Schmidt
4. R. Duman
5. Anita E. Autry
6. Eero Castrén
7. M. Whitman
8. C. Greer

In Developmental Neuroscience

1. L. Monteggia
2. H. Schmidt
3. T. Rantamäki
4. Eero Castrén
5. R. Duman
6. Anita E. Autry
7. C. Greer
8. M. Whitman

Citations in the corpus

• The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity (2010, background): “In contrast to the unclear association with the pathophysiology of depression, there is clear evidence that BDNF signaling through TrkB is involved in the mechanisms of action of antidepressant drugs (Duman and Monteggia, 2006; Castrén et al., 2007; Martinowich et al., 2007).”
• Adult neurogenesis and the olfactory system. (2009, background): “Neurotrophic factors, particularly BDNF and VEGF, are important for the neurogenic mechanisms of antidepressants and environment (Rossi et al., 2006; Castren et al., 2007; Warner-Schmidt and Duman, 2007).”
• Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. (2012, background): “BDNF has been suggested to be involved in the etiopathology of depression (Calabrese et al., 2009; Castrén et al., 2007; Duman and Monteggia, 2006; Kunugi et al., 2010).”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “Expression of neurotrophic factors is activity-dependent and plays an important role in neuronal plasticity (D’Sa and Duman, 2002; Castren et al., 2007).”
• Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders (2012, background): “BDNF and TrkB levels are decreased in regions of the hippocampus in postmortem tissue taken from suicide victims or patients with MDD or in the serum of patients with MDD (Castrén et al., 2007; Castrén and Rantamäki, 2010; Thompson Ray et al., 2011).”
• Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior (2008, background): “1 s; n 12), indicating that newborn neurons permit selected changes in adult brain function (17, 31).”
• GDNF, NGF and BDNF as therapeutic options for neurodegeneration. (2013, background): “, 2012) and depression (Castren et al., 2007).”