Risk alleles for multiple sclerosis identified by a genomewide study.

By David A. Hafler, Alastair Compston, S. Sawcer, Eric S. Lander, Mark J. Daly, P. D. De Jager, P. D. de Bakker, Stacey Gabriel, D. Mirel, A. Ivinson and 9 more. New England Journal of Medicine, 2007

1,623 citations recorded by the source corpus.

Subfields: Immunology, Pathology and Forensic Medicine, Rheumatology

View Paper: https://www.semanticscholar.org/paper/3881afc4e8a93b226c58cfca2c942712d4442a52

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. J. O’Shea
2. Jinfang Zhu
3. Y. Kanno
4. A. Laurence
5. J. Goverman
6. David A. Hafler
7. Howard L. Weiner
8. L. Piccio

In Pathology and Forensic Medicine

1. Jorge R. Oksenberg
2. J. Goverman
3. David A. Hafler
4. Stephen L. Hauser
5. Jinfang Zhu

In Rheumatology

1. Mark J. Daly
2. Stephen L. Hauser
3. J. O’Shea

Citations in the corpus

• Opposing regulation of the Il17 locus through direct, reciprocal actions of STAT3 and STAT5 (2011, background): “Work devoted to the identification of genetic predispositions to autoimmunity has shown that polymorphisms in the Il2ra locus are a relevant factor for type I diabetes and multiple sclerosi”
• Autoimmune T cell responses in the central nervous system (2009, background): “The similarities between CD4 + T cell-mediated EAE and multiple sclerosis and the strong association of certain MHC class II molecules with genetic susceptibility to multiple sclerosi”
• Human genetic variation and its contribution to complex traits (2009, background): “Likewise, many of the loci associated with multiple sclerosis involve immune function — including the interleukin receptor genes IL2RA and IL7RA , and the HLA-DRA locus — but a gene encoding a protein involved in axonal function, kinesin family member 1B ( KIF1B ), is also associated with this ”