B cell development pathways.
By R. Hardy, K. Hayakawa. Annual Review of Immunology, 2001
1,312 citations recorded by the source corpus.
Subfields: Hematology, Immunology
View Paper: https://www.semanticscholar.org/paper/37bb8ceb68870a94d20cb20d5d5c50da515ce662
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In Hematology
In Immunology
Citations in the corpus
- Regulation of plasma-cell development (2005, background): “The presence of surface IgM is required to pass the second check-point, which then allows negative selection to occur (in which tolerance mechanisms delete, anergize or edit autoreactive clones”
- Control of lymphocyte development by nuclear factor-κB (2005, neutral): “These cells then begin to cycle and are referred to as large pre-B cells, using the Hardy nomenclatur”
- Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. (2008, neutral): “on the other, is still fragmentary (Busslinger, 2004; Hardy and Hayakawa, 2001).”
- B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. (2005, background): “B-1 lymphocytes represent a unique B cell population distinguished from conventional B (B-2) cells by their phenotype, anatomical localization, self-renewing capacity, and production of natural antibodies (Berland and Wortis, 2002; Hardy and Hayakawa, 2001).”
- Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70− (2011, background): “…expression of the 67-kD pan–T-cell antigen CD5 was first detected on the surface of certain human and murine malignancies 30 yr ago, and was subsequently identified on a subset of normal B cells in both species (Kantor and Herzenberg, 1993; Morris and Rothstein, 1994; Hardy and Hayakawa, 2001).”
- Cracking the BAFF code (2009, background): “The elimination or reprogramming of self-reactive B cells through B cell receptor (BCR) editing takes place during B cell development in the bone marrow, during B cell maturation in the spleen and most probably after B cell activation, following affinity maturation in the germinal centr”
- The complement system in regulation of adaptive immunity (2004, background): “B1 cells, which are the chief source of natural antibody, are positively selected during early development and are thought to be self-replenishing, unlike conventional B cell”
- Age-related changes in lymphocyte development and function (2004, background): “Cells at these stages of development can be identified based on expression of various cell surface determinant”