Recombinational DNA double-strand breaks in mice precede synapsis
By S. Mahadevaiah, James M. A. Turner, F. Baudat, E. Rogakou, P. Boer, J. Blanco‐Rodríguez, M. Jasin, Scott Keeney, W. Bonner, P. Burgoyne. Nature Genetics, 2001
898 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/3636aab9b2ac1cfdba91e6e680015e45ca9b87cd
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In Cancer Research
- Michael J Hendzel
- John C. Marioni
- Gregory J. Hannon
- Haifan Lin
- I. H. Ismail
- Fabian J Theis
- Rahul Satija
In Molecular Biology
- Gregory J. Hannon
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- O. Fernández-Capetillo
- C. Martinez-Jimenez
- Michael J Hendzel
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- John C. Marioni
Citations in the corpus
- The γ‐H2A.X: Is it just a surrogate marker of double‐strand breaks or much more? (2008, background): “X phosphorylation appears at sites of DSBs during DSB repair, meiotic recombination [Hunter et al., 2001; Mahadevaiah et al., 2001], apoptotic digestion [Rogakou et al.”
- Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis (2018, background): “Multiple variants of H3 and H2A are expressed in spermatocytes (Greaves et al., 2006; Mahadevaiah et al., 2001; Tang et al., 2015), and our data showed that many of these histones are highly expressed in early round spermatids.”
- Mili, a mammalian member of piwi family gene, is essential for spermatogenesis (2004, background): “844 accumulates in the sex body (Mahadevaiah et al., 2001).”
- H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. (2003, methodology): “Fluorescent In Situ Hybridization (FISH) Analysis of Meiotic Burgoyne, P.S., Mahadevaiah, S.K., Sutcliffe, M.J., and Palmer, S.J. X-Y Chromosomes (1992a). Fertility in mice requires X-Y pairing and a Y-chromosomal Meiotic chromosome spreads were prepared following standard “spermiogenesis” gene mapp”
- MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. (2007, background): “Phosphorylated histone H2AX (g-H2AX) marks the sites of Spo11-induced DNA double-strand breaks that occur during leptotene (Celeste et al., 2002; Fernandez- Capetillo et al., 2003; Hamer et al., 2003; Mahadevaiah et al., 2001).”
- γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin (2008, background): “This pattern of phosphorylation is independent of meiotic recombination-associated DSBs (112,113), and it is also independent of ATM and DNA-PK (113).”