SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

By C. S. Sullivan, A. Grundhoff, S. Tevethia, J. Pipas, D. Ganem. Nature, 2005

649 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology, Plant Science

View Paper: https://www.semanticscholar.org/paper/339b5767eca5c4b73d9924390df221c182d9de0f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Olivier Voinnet
2. Phillip D. Zamore
3. E. Miska
4. T. Du
5. David P. Bartel
6. Shou-Wei Ding
7. Inés Álvarez-García
8. C. S. Sullivan

In Oncology

1. Olivier Voinnet
2. Shou-Wei Ding
3. K. Rajewsky
4. Changchun Xiao

In Plant Science

1. Olivier Voinnet
2. Shou-Wei Ding
3. Phillip D. Zamore
4. David P. Bartel
5. T. Du
6. E. Miska
7. Inés Álvarez-García
8. A. Grundhoff

Citations in the corpus

• MicroRNA control in the immune system: basic principles. (2009, background): “This reduces the expression of viral T antigens encoded by the early viral mRNAs, enabling the infected cells to evade killing by cytotoxic T cells (Sullivan et al., 2005).”
• Biological functions of microRNAs: a review (2011, background): “It is expressed late in the viral replication cycle, when it acts to degrade early viral mRNAs encoding T antigen, limiting exposure of the infected cell to cytotoxic T lymphocytes [ 54 ].”
• MicroRNA functions in animal development and human disease (2005, background): “In addition, large DNA viruses of the herpesvirus family, including EBV (Pfeffer et al., 2005; Pfeffer et al., 2004) and SV40 (Sullivan et al., 2005), encode viral microRNA genes.”
• Metazoan MicroRNAs (2018, background): “, 2011), and a few viral mRNAs (Sullivan et al., 2005; Barth et al., 2008), and examples of endogenous miRNA-directed slicing have yet to be reported in nonmammalian bilaterian animals.”
• A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. (2006, methodology): “Recently, we developed a computer algorithm (virMir) to predict virally encoded miRNAs and successfully applied the program to identify miRNAs encoded by Simian Virus 40 (Sullivan et al. 2005).”
• microPrimer: the biogenesis and function of microRNA (2005, background): “Human viruses also express their own miRNAs (Pfeffer et al., 2004; Cai et al., 2005; Pfeffer et al., 2005; Sullivan et al., 2005).”
• Antiviral immunity directed by small RNAs. (2007, positive): “Cis effects are illustrated by SV40-encoded miRNAs that mediate slicing of the perfectly complementary SV40 early transcripts (Sullivan et al., 2005).”
• MicroRNAs in Common Human Diseases (2012, background): “Soon after, dozens of viral miRNAs were identified in polyoma virus[61], adenovirus [62], and several subtypes of the herpes viruses by cloning, bioinformatics, or combined approaches [63–65].”