Seizures Accelerate Functional Integration of Adult-Generated Granule Cells

By Linda Overstreet-Wadiche, Daniel A. Bromberg, AeSoon Bensen, G. Westbrook. 2006

273 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Developmental Neuroscience

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Citations in the corpus

Modification of hippocampal circuitry by adult neurogenesis (2012, background): “, 2006) or marked in transgenic reporter mice (Overstreet et al., 2004; Overstreet-Wadiche et al., 2006; Markwardt and Overstreet-Wadiche, 2008; Markwardt et al., 2009).”
Adult hippocampal neurogenesis in depression (2007, background): “Pilocarpine-induced seizures cause accelerated maturation of new neuron”
Visualization and genetic manipulation of adult neurogenesis using transgenic mice (2011, background): “Comparison of neonatal and adult eGFP+ newborn granule cells in POMC-eGFP mice also revealed a developmental delay in the adult cells despite similar morphological characteristics (Overstreet-Wadiche et al., 2006a).”
Reelin Regulates Neuronal Progenitor Migration in Intact and Epileptic Hippocampus (2007, background): “…upregulated subgranular zone (SGZ) cell proliferation or DGC neurogenesis (Bengzon et al., 1997; Parent et al., 1997, 1998; Gray and Sundstrom, 1998; Scott et al., 1998; Nakagawa et al., 2000; Hattiangady et al., 2004; Mohapel et al., 2004; Jessberger et al., 2005; Overstreet-Wadiche et al., 2006).”
The Developmental Stage of Dentate Granule Cells Dictates Their Contribution to Seizure-Induced Plasticity (2010, background): “Dentate granule cells born 2– 4 weeks before or 4 d after SE form hilar basal dendrites, whereas only DGCs born after SE migrate ectopically Evidence suggests that both mature and immature or newborn DGCs contribute to seizure-induced plasticity in adult rodents (Parent et al., 1999; Overstreet-Wadi”
Epigenetic Modulation of Seizure-Induced Neurogenesis and Cognitive Decline (2007, background): “Previous studies suggested that extensive basal dendrites might contribute to recurrent excitatory circuits interfering with normal synaptic transmission (Ribak et al., 2000; Dashtipour et al., 2003; Overstreet-Wadiche et al., 2006; Shapiro and Ribak, 2006).”
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212 (2009, unknown): “For example, neuronal activation through seizures accelerates the tempo of adult neurogenesis (Overstreet-Wadiche et al., 2006), and prolonged seizures induce inappropriate integration of new neurons into the adult hippocampal circuitry (Jessberger et al., 2007).”
Hippocampal granule cells opt for early retirement (2010, background): “…paradigm, can be observed to occur from 2 weeks to 5 months (Wang et al., 2000; Snyder et al., 2001; van Praag et al., 2002; Ambrogini et al., 2004; Schmidt-Hieber et al., 2004; Esposito et al., 2005; Ramirez-Amaya, 2005; Song et al., 2005; Ge et al., 2006; Overstreet-Wadiche et al., 2006a,b).”
Seizure-Associated, Aberrant Neurogenesis in Adult Rats Characterized with Retrovirus-Mediated Cell Labeling (2007, background): “Basal dendrites arising from aberrant granule neurons might receive aberrant polysynaptic input by mossy fiber connections resulting in heightened excitability and disturbance of information processing through the dentate circuitry (Overstreet-Wadiche et al., 2006).”
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. (2007, background): “Interestingly, neuronal activation, such as seizures, accelerates integration of new neurons in the adult hippocampus (Overstreet-Wadiche et al., 2006b).”
Integration of New Neurons into Functional Neural Networks (2006, background): “…by physical exercise or other behavioral stimulation administered in previous experiments (van Praag et al., 2002), an issue that is especially relevant given recent evidence that the functional maturation of new neurons in the adult brain is activity dependent (Overstreet-Wadiche et al., 2006b).”