Epigenetics: A Landscape Takes Shape

By Aaron D Goldberg, C. D. Allis, E. Bernstein. Cell, 2007

2,452 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/2f914d785b4de0d050dc7c5a64869833ec2d51b1

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Citations in the corpus

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men (2008, background): “First, chromatin research has exploded over the past 10–15 years and HDACs have a key role in deacetylating nucleosomes , interacting with other chromatin regulators and shaping epigenetic landscape”
Epigenetic events in mammalian germ-cell development: reprogramming and beyond (2008, background): “jpg" NDATA ITEM> ]> Epigenetics refers to a collection of mechanisms and phenomena that define the phenotype of a cell without affecting the genotyp”
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention (2007, background): “…of us have excitingly witnessed, the field has experienced an exponential growth in the past decade and is gradually reaching its maturity (Figure 2) (reviewed by Jenuwein and Allis, 2001; Lin and Dent, 2006; Goldberg et al., 2007; Kouzarides, 2007; Li et al., 2007; Shahbazian and Grunstein, 2007).”
Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer (2009, positive): “We therefore surveyed the mRNA expression levels of a series of ‘‘epigenetic’’ modulators that have been implicated in genome instability ( Goldberg et al., 2007 ).”
Extraction, purification and analysis of histones (2007, background): “were known transcriptional regulators prefaced an explosion in histone and chromatin research in the past decad”
Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells (2014, background): “Whole-genome maps of chromatin marks Many chromatin marks are highly correlated with gene activity (Goldberg et al. 2007), raising the possibility that they could play a role in the differential behavior between occluded and activatable genes.”
Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis (2010, background): “Epigenetic changes also affect cell lineage commitment and phenotypic stability by controlling transcription of essential genes (Goldberg et al., 2007).”
Integrated single-cell analysis maps the continuous regulatory landscape of human hematopoietic differentiation (2018, background): “In 1957, ConradWaddington developed an influential analogy for developmental cell biology by conceptualizing cellular differentiation as a ball rolling down a bifurcating three-dimensional surface (Goldberg et al., 2007;Waddington, 1957).”
Child health, developmental plasticity, and epigenetic programming. (2011, background): “of DNA methylation, histone modifications, and various DNA-binding proteins (49, 125).”
Multivalent engagement of chromatin modifications by linked binding modules (2007, background): “Phenotypic traits that are not encoded in the Watson–Crick base pairing of the genome are collectively referred to as epigenetic phenomena and appear to manifest physically as the faithful heritability of chromatin states by daughter cell”
Gender differences in autoimmune disease. (2014, positive): “ylation, histone modification and micro RNA (miRNA) profile (Goldberg et al., 2007; Jiang et al., 2004; Lu, 2013).”