Bacterial Persistence as a Phenotypic Switch

By Nathalie Q. Balaban, J. Merrin, R. Chait, Lukasz Kowalik, Stanislas Leibler. Science, 2004

2,928 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/2f7ce1e54638f1b4c737e91b929eec814b938720

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In Biomedical Engineering

Citations in the corpus

Stochasticity and Cell Fate (2008, background): “is the persister state, which is observed in E. coli and many other bacteria, including pathogenic bacteria [21, 22 ].”
Persisters: a distinct physiological state of E. coli (2006, background): “(page number not for citation purposes) which account for the majority of infectious diseases in the developed world [6,7].”
Cellular Decision-Making and Biological Noise: From Microbes to Mammals (2011, background): “Persistence of E. coli cells has been observed at the single-cell level (Balaban et al., 2004), but the underlying network and molecular mechanisms may be highly complex and are currently unknown.”
Multidrug tolerance of biofilms and persister cells. (2008, background): “coli hipA7 strain (Balaban et al. 2004).”
Bistability in bacteria (2006, background): “Importantly, experiments with hip mutants have revealed that a small number of cells in the population spontaneously enter (and later exit) a state of no or slow growth and do so prior to drug treatment (Balaban et al., 2004).”
Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters (2014, neutral): “References and Notes 1. N. Q. Balaban, J. Merrin, R. Chait, L. Kowalik, S. Leibler, Science 305, 1622–1625 (2004). 2. J. W. Bigger, Lancet 244, 497–500 (1944). 3. I. Keren, D. Shah, A. Spoering, N. Kaldalu, K. Lewis, J. Bacteriol. 186, 8172–8180 (2004). 4. N. Q. Balaban, K. Gerdes, K. Lewis, J. D. M”
Tumor heterogeneity: causes and consequences (2009, background): “Observation of single-cell dynamics with the help of microfluidic devices has linked persistence with reduced proliferation rates [21].”
A chromatin-mediated reversible drug tolerant state in cancer cell subpopulations (2010, background): “This is highly reminiscent of the properties of antibiotic-tolerant bacterial subpopulations, also called ‘‘persisters,’’ which similarly exhibit a transient ability to endure potentially lethal stresses (Balaban et al., 2004; Dhar and McKinney, 2007).”
Physiological heterogeneity in biofilms (2008, background): “gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=12319"> Escherichia coli at the single-cell leve”
Specialized Persister Cells and the Mechanism of Multidrug Tolerance in Escherichia coli (2004, background): “coli were shown to be nongrowing cells (3).”