Translational control by MAPK signaling in long-term synaptic plasticity and memory.

By R. J. Kelleher, A. Govindarajan, Hae-yoon Jung, Hyejin Kang, S. Tonegawa. Cell, 2004

883 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/2e8c166a47a87f62348b5715700c47d83113f1f5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Nahum Sonenberg
2. S. Tonegawa
3. E. Schuman
4. M. A. Sutton
5. R. J. Kelleher
6. Mark F. Bear
7. T. McHugh
8. A. Govindarajan

In Cognitive Neuroscience

1. S. Tonegawa
2. Nahum Sonenberg
3. T. McHugh
4. Mark F. Bear
5. Joel D. Richter
6. N. Hay
7. Douglas A. Baxter
8. John H. Byrne

In Neurology

1. Nahum Sonenberg
2. E. Schuman
3. Mark F. Bear
4. S. Tonegawa
5. A. Govindarajan
6. E. T. Rolls

Citations in the corpus

• Compartmentalizing the neuronal plasma membrane from axon initial segments to synapses. (2009, background): “Other proteins that regulate mRNA translation initiation are cap-binding protein eIF4E and eIF4E binding protein (eIF4E-BP) (Banko et al., 2005; Kelleher et al., 2004; Scheper and Proud, 2002; Sonenberg and Dever, 2003).”
• Regulatory mechanisms of AMPA receptors in synaptic plasticity (2007, background): “LTP is suppressed to an equivalent degree by either the protein synthesis inhibitor anisomycin or the expression of a dominant-negative MEK (dnMEK”
• NMDA receptors, place cells and hippocampal spatial memory (2004, background): “Additional regulation can also occur at the level of mRNA transport and translatio”
• Translational control of long-lasting synaptic plasticity and memory. (2009, neutral): “…is induced with electrical or chemical stimulation, is dependent on new gene expression, as it is blocked by both transcription and translation inhibitors (for reviews see Costa-Mattioli and Sonenberg , 2008; Kandel, 2001; Kelleher et al., 2004b; Klann and Dever, 2004; Sutton and Schuman, 2006).”
• Upstream and downstream of mTOR. (2004, background): “A leading model for the cellular plasticity underlying learning is long-term potentiation (LTP), in which the pairing of input stimulation and postsynaptic depolarization leads to long-term increases in the strength of the synaptic connection between input and output.”
• Spacing Effect: SHP2 Phosphatase Regulates Resting Intervals Between Learning Trials in Long-Term Memory Induction (2009, neutral): “In addition, MAPK activity has been implicated in memory formation in invertebrates and vertebrates ( Kandel, 2001; Kelleher et al., 2004; Cammarota et al., 2007; Mayford, 2007).”
• Translational regulatory mechanisms in persistent forms of synaptic plasticity. (2004, background): “not the maintenance of long(Otani et al., 1989; Huang and Kandel, 1994; Frey and Morris, 1997; Scharf et al., 2002; Kelleher et al., 2004).”
• Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity (2008, neutral): “Induction of LTP enhances phosphorylation of these factors (Kelleher et al., 2004; Schmitt et al., 2005), and mice expressing dnMEK1 show an impairment in L-LTP and in phosphorylation of these translation factors (Kelleher et al., 2004).”
• The autistic neuron: troubled translation? (2008, background): “Supporting this notion, multidisciplinary studies in mice have demonstrated that defects in synaptic protein synthesis impair hippocampal learning and memory (Kelleher et al., 2004a; Costa-Mattioli et al., 2007).”
• Regulation of cap-dependent translation by eIF4E inhibitory proteins (2005, methodology): “Studies using rapamycin indicate that FRAP/mTOR signalling is involved in establishing the ta”
• Control of Dendritic Arborization by the Phosphoinositide-3′-Kinase–Akt–Mammalian Target of Rapamycin Pathway (2005, neutral): “Guinea pig postsynaptic density-95 (PSD-95) antiserum was described previously (Kim et al., 1995).”