Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

By Li Ma, J. Teruya-Feldstein, R. Weinberg. Nature, 2007

1,687 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/2dc7a4de9a72a06b5b2ec92f5028f93538a37cb4

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Citations in the corpus

Epithelial-mesenchymal transitions: insights from development (2012, background): “Recent findings for JmjD2A in chicken and Wt1 in mouse have increased the repertoire miR-200 family Zeb1, Zeb2 E-cadherin Akt1/Akt2 ratio Gata3 Snail1 TGFβ Trps1 miR-221 and miR-222 Fosl1 MEK miR-661 Nectin-1, StarD10 EMT miR-10b Hoxd10 RhoC activation Jag2 Notch miR30a Fig.”
MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer (2015, background): “miR-9, miR10b, miR-29a, miR-96, miR-146a, miR-181, miR-373, miR-375, miR-520c, miR589 BC cell lines [162-165, 167, 198, 199]”
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations (2008, neutral): “that promotes cell migration and invasion (22).”
EMT and tumor metastasis (2015, neutral): “4% TGF-β, BMP-7, Claudin-1, HDAC1,2,3, hepatocyte growth factor, Klf8, miR-23b, miR-29b, miR-34, miRs-141/200, miR-205, miR-438-3p, [62,66,72-74]”
MicroRNAs in cancer: small molecules with a huge impact. (2009, background): “One of the first studies reporting a prometastatic role for a microRNA was published by Ma et al.(24) They observed that miR-10b was downmodulated in all the breast carcinomas from metastasis-free patients, as previously reported,(18) but surprisingly, 50% of metastasispositive patients had elevated”
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin (2008, background): “Recent findings have confirmed a critical role of miRNA as powerful diagnostic and prognostic indicators of human breast cancer (15, 16, 37, 38, 44), resulting in the develop-”
miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis (2020, background): “It has been shown that its expression in non-metastatic disease induces cell invasion and metastasis, probably by increasing the expression of RhoC (Ras homolog gene family, member C), a known oncogene [125].”
Epithelial-mesenchymal transitions in development and disease. (2009, background): “In addition to the members of the miR200 family, miR-10b, miR-373, and miR-520c have also been implicated in the progression of breast carcinoma (Huang et al., 2008; Ma et al., 2007), and miR-21 is upregulated during TGFβ-induced EMT in tumor cell lines (Zavadil et al.”
A microRNA DNA methylation signature for human cancer metastasis (2008, background): “Recently, a new function mediating tumor metastasis in breast cancer has been assigned to miRNAs, by which this malignant step is promoted (7, 8) or suppressed (9).”