Tryptophan and the immune response

By J. Moffett, M. Namboodiri. Immunology and Cell Biology, 2003

756 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Biological Psychiatry, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/2777dd1fcdc52ff40b636980eb4dfa0cfae1348b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. D. Munn
2. A. Mellor

In Biological Psychiatry

1. F. Quintana
2. D. Munn
3. A. Mellor

Citations in the corpus

• Tolerogenic dendritic cells (2016, background): “rate-limiting enzymes IDO or tryptophan 2,3-dioxygenase (TDO) [81].”
• Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism (2010, background): “These subsequent metabolites along this metabolic pathway—collectively referred to as kynurenines—are created by downstream enzymes that are specifically expressed in different cell types (19).”
• Physiological roles of tryptophan in teleosts: current knowledge and perspectives for future studies (2019, background): “Acroleyl aminofumarate can either be fully 747 oxidized to picolinic acid and acetyl-CoA or it can be spontaneously cyclized to 748 quinolinic acid and subsequently to nicotinamide and nicotinic acid (Fernstrom, 2016; 749 Grohmann et al., 2003; Moffett & Namboodiri, 2003a).”
• The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells1 (2006, background): “In addition, it has been suggested that quinolinate, a tryptophan catabolite, functions to replenish nicotinamide adenine dinucleotide in leukocytes, which is depleted by oxidative stress during an immune response (47).”
• Biological roles of tryptophan and its metabolism: Potential implications for pig feeding (2007, background): “During the last decade, the involvement of tryptophan in the control of immune response has been fully documented (Moffett and Namboodiri, 2003).”