A quantitative atlas of mitotic phosphorylation

By Noah E. Dephoure, Chunshui Zhou, J. Villén, S. Beausoleil, C. Bakalarski, Stephen J. Elledge, Steven P. Gygi. Proceedings of the National Academy of Sciences of the United States of America, 2008

1,681 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/266d0b42f13b63162be3be4223714cd72880bb9a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

In Molecular Biology

In Oncology

Citations in the corpus

Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate. (2014, background): “Also, acetylation of two lysine residues within the SRA was found (Choudhary et al., 2009; Dephoure et al., 2008; Olsen et al., 2010; Rigbolt et al., 2011).”
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB (2012, background): “In a recent high throughput mass spectrometry study, TFEB was predicted to be phosphorylated at 11 different residues, thus suggesting a complex regulation of its activity with several phosphorylation sites potentially involved (Dephoure et al , 2008).”
From promiscuity to precision: protein phosphatases get a makeover. (2009, background): “…stable isotope labeling combined with high accuracy mass spectrometry to analyze protein phosphorylation in cells during mitosis and following DNA damage identified more than 1,000 phosphoproteins, including all the PP1 catalytic subunits and many PP1 and PP2A regulators (Dephoure et al., 2008).”
Decoding signalling networks by mass spectrometry-based proteomics (2010, background): “Phosphorylation changes between mitotically arrested and interphase cell”
Proteomics by mass spectrometry: approaches, advances, and applications. (2009, background): “Recent studies quantified both phosphorylation levels and protein levels for mitotic phosphorylation (223), cell cycle kinases (251), and the beta-adrenergic pathway (206) (Figure 6).”
The endoplasmic reticulum: structure, function and response to cellular signaling (2015, background): “Interestingly, phosphorylation of STIM1 also blocks activation of SOCE, although this occurs independently of the STIM1:EB1 interaction [118].”
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes (2016, background): “Importantly, two independent global phosphorylation studies demonstrated that these two serine residues in NCoR are phosphorylated in cells (43,44).”
Multidimensional proteomics for cell biology (2015, background): “These studies have provided crucial insights into the regulation of protein properties during fundamental processes, such as cell cycle progression 83,84 , and into signalling mechanisms that affect cellular pathways, such as the epidermal growth factor signalling cascade 85 .”
Applying mass spectrometry-based proteomics to genetics, genomics and network biology (2009, background): “Several studies recently showed that thousands of new protein phosphorylation sites could be identified from low sample amount”