Highly Permissive Cell Lines for Subgenomic and Genomic Hepatitis C Virus RNA Replication

By K. Blight, J. McKeating, Charles M. Rice. Journal of Virology, 2002

1,292 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/255b9ea21e153c407073ddae3c7ca64f686210ea

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Eileen M. Foy
2. Brett D. Lindenbach Heinz-J
3. G. Randall
4. Nicholas S. Heaton
5. M. Gale
6. Charles M. Rice
7. Kui Li
8. R. Sumpter

In Hepatology

1. Eileen M. Foy
2. Brett D. Lindenbach Heinz-J
3. Charles M. Rice
4. M. Gale
5. G. Randall
6. Nicholas S. Heaton
7. B. Lindenbach
8. D. Moradpour

In Radiology, Nuclear Medicine and Imaging

1. G. Randall
2. Nicholas S. Heaton
3. M. Gale
4. Charles M. Rice
5. Eileen M. Foy

Citations in the corpus

• Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I (2005, methodology): “5 cells are derived from and are isogenic to Huh7 cells (3).”
• Dengue virus induced autophagy regulates lipid metabolism (2010, methodology): “5 cells, a subline derived from the hepatocyte Huh7 cell line (Blight et al., 2002), were primarily used in this study.”
• Evasion of intracellular host defence by hepatitis C virus (2005, background): “, including cells that are highly permissive to HCV RNA replicatio”
• Replication of hepatitis C virus (2007, background): “In addition, the efficiency of replicon RNA amplification was found to be determined by selection for particularly permissive cells within a given population of Huh-7 cell”
• Unravelling hepatitis C virus replication from genome to function (2005, background): “Although full-length genomes harbouring adaptive mutations replicated efficiently in Huh-7 cells and expressed the structural proteins, infectious particles were not release”
• Flaviviridae :T he Viruses and Their Replication (2007, background): “This is important, because RIG-I activation has been shown to inhibit HCV replication (684), and a dominant negative mutation in RIG-I renders an Huh-7 subline highly permissive for HCV RNA replication (61,684).”
• The endocytic recycling compartment serves as a viral factory for hepatitis E virus (2021, methodology): “5 [13] cells were authenticated by STR profiling and Multiplex Cell Authentication 11 (Multiplexion) respectively, and cultured as previously described [14].”