The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

By A. Elkaoutari, Fabrice Armougom, Jeffrey I. Gordon, Didier Raoult, Bernard Henrissat. Nature Reviews Microbiology, 2013

1,491 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/2498fa6bb2acf63abe1d430fc0d7a60a8b9eecbf

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In Genetics

1. Stuart E. Jones
2. J. Lennon
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4. J. Martiny
5. C. Pedrós-Alió

In Molecular Biology

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In Nutrition and Dietetics

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Citations in the corpus

• Colonocyte metabolism shapes the gut microbiota (2018, neutral): “Members of the classes Clostridia (phylum Firmicutes) and Bacteroidia (phylum Bacteroidetes), which dominate the community of obligate anaerobic bacteria in the adult colon, provide benefit because they encode a broad spectrum of enzymes for hydrolyzing different complex carbohydrates (14).”
• Microbiomes in light of traits: A phylogenetic perspective (2015, background): “ability to degrade particular carbohydrates (79) and bile tolerance (77).”
• Bifidobacteria and Their Role as Members of the Human Gut Microbiota (2016, background): “Fifteen out of the 20 patients remained in remission throughout the trial, suggesting that administration of this bacterial cocktail is beneficial in maintaining remission from ulcerative colitis (Venturi et al., 1999; Gionchetti et al., 2000).”
• Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers (2018, background): “, binding to starch granules [24]) or the presence of DNA sequences encoding amylaselike GH13 domains (25).”
• Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut (2016, background): “Compared with the human genome, encoding only 17 glycoside hydrolases for the digestion of food carbohydrates, bifidobacterial genomes possess high numbers of genes encoding these carbohydrases (El Kaoutari et al., 2013).”
• American Gut: an Open Platform for Citizen Science Microbiome Research (2018, neutral): “Because bacteria differ in their carbohydrate binding modules and enzymes that hydrolyze diverse substrates in the gut (28), a diet containing various types of dietary fibers and resistant starches likely supports a more diverse microbial community (29, 30).”
• A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility (2016, neutral): “While the ability to annotate CAZyme functions is well developed vis-a-vis many other metabolic functions that are important in the microbiome (El Kaoutari et al., 2013), there are still substantial ambiguities in connecting such predictions with precise catalytic roles.”
• Gut Microbiota Orchestrates Energy Homeostasis during Cold. (2015, neutral): “The higher fecal caloric content after complete microbiota depletion was confirmed using bomb calorimetry (Figure S1G) and was consistent with previous reports (El Kaoutari et al., 2013), suggesting lower energy harvest from the food.”