The oligodendrocyte precursor cell in health and disease.

By J. Levine, R. Reynolds, J. Fawcett. Trends in Neurosciences, 2001

686 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/1f76336b0ce8849c3d745d57ec946ea9fbd3f1e0

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In Cellular and Molecular Neuroscience

In Developmental Neuroscience

In Neurology

Citations in the corpus

Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains (2002, background): “Occasionally, cells that exhibited the characteristic morphology of either oligodendrocytes or oligodendrocyte precursor cells in CA1 stratum radiatum were filled, possessing small, round somata and radial, varicose processes (D’Ambrosio et al., 1998; Levine et al., 2001).”
Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system (2016, neutral): “Although OPCs in different regions of the CNS have been described to have different morphologies (26), we were unable to identify region-specific subpopulations of OPCs in our dataset (Fig.”
New concepts in the immunopathogenesis of multiple sclerosis (2002, neutral): “During the resolution of lesions, oligodendrocyte progenitor cells enter the area of demyelination, expand and develop into myelinating oligodendrocyte”
Chordin-induced lineage plasticity of adult SVZ neuroblasts after demyelination (2010, positive): “In postnatal and adult brain, NPCs that generate oligodendrocytes migrate from SVZ to developing white matter, where they stop dividing, differentiate and myelinate axon”
Remyelination in the CNS: from biology to therapy (2008, background): “These multiprocessed proliferating cells are widespread throughout the CNS, occurring in both white matter and grey matter at a density similar to that of microglial cells (5–8% of the cell population”
NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration. (2010, background): “NG2 cells are mitotically active and exhibit enhanced proliferation in response to acute CNS injury, ischemia, and demyelination (Levine et al., 2001).”