Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal.

By Patrice D Cani, E³ Lecourt, E. Dewulf, Florence M. Sohet, B. Pachikian, D. Naslain, F. D. de Backer, A. Neyrinck, N. Delzenne. American Journal of Clinical Nutrition, 2009

766 citations recorded by the source corpus.

Subfields: Molecular Biology, Nutrition and Dietetics, Physiology

View Paper: https://www.semanticscholar.org/paper/1a741db25d997b463086d6331874af06907f517d

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Citations in the corpus

Effects of Gut Microbes on Nutrient Absorption and Energy Regulation (2012, background): “The ingestion of oligofructose has been demonstrated to result in a reduction of food intake(145) and a decrease in body weight(146) in mice, as well as weight loss and satiety in humans.(147,148) Weight loss due to oligofructose supplementation has been associated with colonic fermentation of oligo”
Impact of the gut microbiota on inflammation, obesity, and metabolic disease (2016, result): “Randomized controlled studies have identified surrogate markers of prebiotic treatment (such as plasma PYY, GLP-1, ghrelin) to be negatively correlated with weight gain, inflammation, and impaired glucose metabolism, which support the mechanisms observed in rodents [89, 90].”
Short chain fatty acids in human gut and metabolic health. (2020, neutral): “Cani et al. (2009a) showed that a 2-week treatment with oligofructose (16 g/day) decreased postprandial glucose levels, which was associated with plasma GLP-1 levels and an increased breath-hydrogen excretion (increased microbial fermentation) in healthy adults.”
Role of the microbiome in human development (2019, background): “51 Butyrate and acetate regulate satiety, 66 67 with acetate being obesogenic.”
Targeting gut microbiota in obesity: effects of prebiotics and probiotics (2011, background): “Interestingly, a 2-week treatment with inulin-type fructans (16 g per day) in healthy volunteers increased the postprandial release of gut peptides (namely GLP-1 and gastric inhibitory peptide), to modify eating behavior (increased satiety and decreased calorie intake) and decrease postprandial glyc”
Lentil (Lens culinaris L.): A prebiotic-rich whole food legume (2013, background): “Prebiotics may contribute to dietary strategies to reduce obesity (Cani et al., 2009; Parnell & Reimer, 2009).”
Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion* (2013, background): “GLP-1 secretion has been associated with gut flora modulation in other studies (49).”