Targeting gut microbiota in obesity: effects of prebiotics and probiotics

By N. Delzenne, A. Neyrinck, F. Bäckhed, Patrice D Cani. Nature Reviews Endocrinology, 2011

743 citations recorded by the source corpus.

Subfields: Gastroenterology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/5d7db7b4a89805691d375ab665de700bd1ba1f44

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Gastroenterology

1. Julian R. Marchesi
2. F. Bäckhed

In Molecular Biology

1. Patrice D Cani
2. F. Bäckhed
3. Herbert Tilg
4. N. Delzenne
5. A. Neyrinck
6. M. Conlon
7. A. Bird
8. V. Tremaroli

In Physiology

1. Patrice D Cani
2. F. Bäckhed
3. N. Delzenne
4. A. Neyrinck
5. Herbert Tilg
6. Liping Zhao
7. V. Tremaroli
8. M. Conlon

Citations in the corpus

• Role of intestinal microbiota and metabolites on gut homeostasis and human diseases (2017, background): “From the metabolic viewpoint, gut microbiota may be recognized as a consortium capable of modulating host physiology and immunity [146].”
• Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity (2014, background): “Probiotics and prebiotics are known to improve the composition of the gut microbiota in favor of bacteria that decrease gut-barrier alterations (50, 68) and inflammation (13, 69), and they may improve mood and behavior in several pathological contexts (27, 70–73).”
• Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism (2013, background): “Overall, our findings point to the potential therapeutic efficacy of drugs that alter gut microbiota, particularly to prevent or treat metabolic disease (Delzenne et al., 2011).”
• Diversity of Bifidobacteria within the Infant Gut Microbiota (2012, background): “Furthermore, microbial dysbiosis has been linked to several functional gut disorders, such as inflammatory bowel disease [4,5], irritable bowel syndrome [6], stomach cancer [7], mucosa-associated lymphoid tissue lymphoma [8], obesity [9,10] and necrotizing enterocolitis [11].”
• Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice (2014, background): “Oral delivery of probiotic bacteria has been used as a gut microbiota-targeted strategy to combat MS (Delzenne et al., 2011).”
• Intestinal permeability – a new target for disease prevention and therapy (2014, background): “In addition, administration of selected prebiotics or probiotics can improve metabolic alterations in animal models of metabolic liver disease [103,127] and in obese human individuals [234,235].”
• Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion* (2013, background): “Probiotics transmit their major effects through the modulation of the gut flora (40).”
• The Impact of Diet and Lifestyle on Gut Microbiota and Human Health (2014, background): “, CRC, IBD, type 2 diabetes, obesity) by preventing colonization by enteric pathogens [61,158,161].”