Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

By R. Panush. 2011

634 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Genetics, Neurology

View Paper: https://www.semanticscholar.org/paper/178c8f1a8e191c375afcee77e11b8ebbb84d6761

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. A. J. Brown
2. N. Gow
3. Mihai G. Netea
4. F. L. van de Veerdonk
5. S. Gaffen
6. A. Garg

In Genetics

1. A. J. Brown
2. N. Gow
3. Mihai G. Netea
4. D. Artis
5. F. L. van de Veerdonk
6. S. Gaffen
7. A. Garg

In Neurology

1. A. J. Brown
2. N. Gow
3. Mihai G. Netea
4. F. L. van de Veerdonk
5. S. Gaffen
6. A. Garg

Citations in the corpus

• Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22 (2011, background): “This impairment in IL-22 production correlates with the development of chronic mucocutaneous candidiasis in these patient”
• IL-17 Signaling: The Yin and the Yang (2017, background): “Individuals with AIRE gene deficiency can also generate neutralizing autoantibodies against Th17 cytokines including IL-17A, and the presence of these antibodies is typically associated with CMC as well [26, 27].”
• Homeostatic immunity and the microbiota (2017, neutral): “deficiencies that not only display increased ecological permissiveness but also often suffer from infections caused by normal constituents of the microbiota (Puel et al., 2010; Smeekens et al., 2014).”
• Candida albicans morphogenesis and host defence: discriminating invasion from colonization (2011, positive): “By contrast, patients with APECED were found to have neutralizing autoantibodies against T H 17-type cytokine”
• Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. (2013, positive): “In combination with IL-17A, IL-22 mediates a pivotal innate antifungal resistance in mice (De Luca et al., 2010) and humans (Puel et al., 2010).”
• Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism (2018, background): “, 2010) and humans (Puel et al., 2010) and provides colonization resistance against the fungus C.”