Candida albicans morphogenesis and host defence: discriminating invasion from colonization
By N. Gow, F. L. van de Veerdonk, A. J. Brown, Mihai G. Netea. Nature Reviews Microbiology, 2011
853 citations recorded by the source corpus.
Candida albicans is a common fungal pathogen of humans that colonizes the skin and mucosal surfaces of most healthy individuals. Until recently, little was known about the mechanisms by which mucosal antifungal defences tolerate colonizing C. albicans but react strongly when hyphae of the same microorganism attempt to invade tissue. In this Review, we describe the properties of yeast cells and hyphae that are relevant to their interaction with the host, and the immunological mechanisms that differentially recognize colonizing versus invading C. albicans.
Subfields: Emergency Medical Services, Epidemiology, Infectious Diseases
View Paper: https://www.semanticscholar.org/paper/f68ccf711851a12b015a5aca68bf1da05748db19
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In Epidemiology
In Infectious Diseases
Citations in the corpus
- Biological roles of glycans (2016, background): “Examples include Candida albicans (441, 958, 959) and Histoplasma capsulatum (960).”