Mobilization of transposons by a mutation abolishing full DNA methylation in Arabidopsis

By A. Miura, Shoji Yonebayashi, Koichi Watanabe, T. Toyama, H. Shimada, T. Kakutani. Nature, 2001

595 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/16bc255933fc7af9bb2f705aeffa365acf4f929d

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In Plant Science

Citations in the corpus

Widespread dynamic DNA methylation in response to biotic stress (2012, background): “Mutants defective in CG or non-CG methylation exhibit numerous developmental pleiotropies arising from organism-wide gene derepression (15, 25) and transposon mobilization (6) (stable or heritable methylation), as well as endosperm-specific defects in gene imprinting (dynamic methylation).”
Gardening the genome: DNA methylation in Arabidopsis thaliana (2005, background): “The clearest demonstration of this has come from the model plant Arabidopsis thaliana, in which it was shown that transposons are mobilized when DNA methylation is reduce”
Plant transposable elements: where genetics meets genomics (2002, unknown): “For example, in the Arabidopsis ddm1 ( decreased DNA methylation 1 ) mutant, endogenous transposons of the Mutator and CACTA ( En / Spm ) superfamilies of class 2 elements are transcriptionally and transpositionally reactivate”
Epigenetic reprogramming and small RNA silencing of transposable elements in pollen (2009, unknown): “Transposition only occurs in mutants that lose both heterochromatic histone modification and DNA methylation, such as ddm1 (Miura et al., 2001; Singer et al., 2001).”
Understanding mechanisms of novel gene expression in polyploids. (2003, background): “Such changes might also lead to transcriptional and transpositional activation of DNA transposons and retrotransposons, as was shown recently for the Arabidopsis DECREASE IN DNA METHYLATION mutant, ddm1 [42-44].”
Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis. (2006, unknown): “Consistent with previous studies, we found a significant enrichment of methylation in heterochromatin and siRNA clusters as well as an important role for methylation in silencing transposons and pseudogenes (Lippman et al., 2004; Miura et al., 2001; Singer et al., 2001).”