A common variant associated with prostate cancer in European and African populations

By L. Amundadottir, P. Sulem, J. Gudmundsson, Agnar Helgason, A. Baker, B. Agnarsson, A. Sigurdsson, K. Benediktsdottir, J. Cazier, J. Sainz and 36 more. Nature Genetics, 2006

733 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/15a878ef61136f7d19a9990c2145d2ab507f4230

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Citations in the corpus

SNPFile – A software library and file format for large scale association mapping and population genetics studies (2008, unknown): “Background High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies [1], in particular genome disease association studies [2-7].”
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24 (2007, background): “Two independent studies previously demonstrated a single nucleotide polymorphism (SNP) in 8q24, rs1447295, is associated with prostate cancer ris”
Human genetic variation and its contribution to complex traits (2009, background): “, and for the variants on 8q24 that are associated with susceptibility to multiple solid tumours this distance is 300 k”
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. (2010, background): “The 8q24 region contains the MYC oncogene, is rich in sequence variants, and was previously shown as a risk factor for several human cancers (Amundadottir et al., 2006; Freedman et al., 2006; Haiman et al., 2007a; Haiman et al., 2007b; Schumacher et al., 2007; Shete et al., 2009; Visakorpi et al., 1”
Molecular genetics of prostate cancer: new prospects for old challenges. (2010, background): “…of a major susceptibility locus at 8q24 in several large-scale genome-wide association studies of prostate cancer as well as other epithelial cancers (Amundadottir et al. 2006; Freedman et al. 2006; Gudmundsson et al. 2007, 2009; Haiman et al. 2007; Yeager et al. 2007, 2009; Al Olama et al. 2009).”
Computer-Aided Detection and diagnosis for prostate cancer based on mono and multi-parametric MRI: A review (2015, background): “The etiology was linked to the following factors [18]: (i) family history [19,20], (ii) genetic factors [21–23], (iii) race-ethnicity [19,24], (iv) diet [19,25,26], and (v) obesity [19,27].”
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24 (2007, background): “Here we report a second genetic variant in the 8q24 region that, in conjunction with another variant we recently discovere”
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 (2007, methodology): “In stage 4, genotypes (9) in the Scottish cohort, which was unrestricted by age, were measured by TaqMan assay.”
Inflammation in prostate carcinogenesis (2007, result): “Although it is currently unknown whether or not 8q24 is related to inflammatory pathways, one very recent example of a success story stems from a set of independent studies that implicated this chromosome region in prostate cancer occurring in both families and in sporadic case”