Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24

By B. Zanke, C. Greenwood, J. Rangrej, Rafal Kustra, A. Tenesa, S. Farrington, J. Prendergast, S. Olschwang, T. Chiang, Edgar Crowdy and 33 more. Nature Genetics, 2007

755 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/1abd198f80b3671b44861adb5bb5ddfd97c8b9bc

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In Cancer Research

1. Edward L. Giovannucci
2. Stephen B. Gruber
3. Ian Tomlinson

In Genetics

1. Elizabeth T. Cirulli
2. Peter Kraft
3. Ian J. Deary
4. Stefan Schreiber
5. David B. Goldstein
6. John P. A. Ioannidis

In Pathology and Forensic Medicine

1. Stephen B. Gruber
2. Edward L. Giovannucci
3. M. Thun
4. E. Calle
5. W. Willett
6. M. F. Holick

Citations in the corpus

• Multiple loci identified in a genome-wide association study of prostate cancer (2008, background): “9 Mb) contained 28 SNPs with P values −3 , but this region was deliberately explored with 192 SNPs drawn from the initial genome scan on the basis of strong prior evidence for associations with breast, colon and prostate cance”
• Uncovering the roles of rare variants in common disease through whole-genome sequencing (2010, background): “For example, when associated SNPs are far from the nearest gene, it is often assumed that a regulatory variant of subtle effect must be the cause, such as for the SNPs in 8q24 that are associated with colorectal cance”
• STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement (2009, neutral): “org 0158 February 2009 | Volume 6 | Issue 2 | e1000022 association studies [85,87–105].”
• Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 (2008, background): “However, recent association studies have shown that common genetic variation in the 8q24 (refs”
• Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer (2008, background): “Recent GWA studies have validated the hypothesis that part of the heritable risk is caused by common, low-risk variants, identifying CRC susceptibility loci mapping to 8q24 (rs6983267”