Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

By M. Yeager, N. Orr, R. Hayes, K. Jacobs, Peter Kraft, S. Wacholder, Mark J Minichiello, Paul Fearnhead, Kai Yu, N. Chatterjee and 25 more. Nature Genetics, 2007

1,160 citations recorded by the source corpus.

Subfields: Genetics, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/23582dcda287ee5140acbea05d0e3d4e889192fc

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Citations in the corpus

• SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies (2009, methodology): “For example, in prostate cancer a confirmed SNP in MSMB from the initial GWAS had a P-value of only 0.042, but the P-value was 7.31 � 10–13 in a follow up study ( 4 ,5).”
• Learning your identity and disease from research papers: information leaks in genome wide association study (2009, background): “These statistics are routinely published in GWAS papers [29, 54, 53, 57, 40].”
• Genome-wide association study identifies five susceptibility loci for glioma (2009, methodology): “For controls, we used Illumina Hap550K-BeadChip genotypes on 2,243 individuals from the Cancer Genetic Markers of Susceptibility studie”
• Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 (2007, background): “This locus has also been implicated in prostate cance”
• Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. (2018, neutral): “The nearer region included additional non-coding genes, as well as the rs6983267 and rs1447295 germline variants associated with prostate cancer risk (Amundadottir et al., 2006; Yeager et al., 2007).”
• MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis (2008, positive): “subsequently replicated by a genome-wide association stud”
• Privacy-Preserving Data Exploration in Genome-Wide Association Studies (2013, methodology): “A study may report individual correlations between SNP pairs of interest [5, 27], or a “heat map” of the correlations among all SNPs in a region [5, 13, 27, 28, 34].”
• Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. (2010, background): “…MYC oncogene, is rich in sequence variants, and was previously shown as a risk factor for several human cancers (Amundadottir et al., 2006; Freedman et al., 2006; Haiman et al., 2007a; Haiman et al., 2007b; Schumacher et al., 2007; Shete et al., 2009; Visakorpi et al., 1995; Yeager et al., 2007).”
• Genetics and biology of prostate cancer (2018, background): “…that prostate cancer is among themost heritable cancers (Lichtenstein et al. 2000); GWASs have identifiedmany prostate cancer susceptibility loci (Yeager et al. 2007; Eeles et al. 2008, 2009, 2013; Thomas et al. 2008;Gudmundsson et al. 2009; Yeager et al. 2009; Takata et al. 2010; Xu et al.…”
• Progress and Promise of Genome-Wide Association Studies for Human Complex Trait Genetics (2011, background): “Trait-associated SNPs may be preferentially located in genic regions, but they can lie anywhere in the genome, including in gene deserts (e.g., the prostate cancer locus at 8q24; Yeager et al. 2007 and the Crohn’s disease locus at 5p13; Wellcome Trust Case Control Consortium 2007).”
• Sequence variants at the TERT- CLPTM1L locus associate with many cancer types (2009, neutral): “…the dataset on colorectal cancer from the U.K. Institute of Cancer Research (ICR) 27 , the dataset on lung cancer from the International Agency for Research on Cancer (IARC) 11 and the datasets on prostate and breast cancer from the Cancer Genetics Markers of Susceptibility (CGEMS) study group 4 .”
• Molecular genetics of prostate cancer: new prospects for old challenges. (2010, background): “…of a major susceptibility locus at 8q24 in several large-scale genome-wide association studies of prostate cancer as well as other epithelial cancers (Amundadottir et al. 2006; Freedman et al. 2006; Gudmundsson et al. 2007, 2009; Haiman et al. 2007; Yeager et al. 2007, 2009; Al Olama et al. 2009).”