The energetics of genome complexity

By N. Lane, William F. Martin. Nature, 2010

1,141 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/158734286ea5ba2d9a9200a565918fad10e4ecdc

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Citations in the corpus

The Logic of Chance: The Nature and Origin of Biological Evolution (2011, methodology): “Simple estimates made by Nick Lane and Bill Martin suggest that the emergence of large, complex cells like those of eukaryotes does not appear energetically feasible without the acquisition of multiple energy-producing organelles capable of autonomous reproduction and regulation (Lane and Martin, 20”
The Multiple Origins of Complex Multicellularity (2011, background): “In a new and different line of reasoning, Lane & Martin (2010) have recently proposed that bacterial genome size is also limited by bioenergetics, a constraint lifted in eukaryotes by mitochondria.”
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. (2011, background): “It has been argued that the endosymbiotic acquisition of aerobic bacteria to form mitochondria was the crucial event in the development of the eukaryotes (Lane and Martin 2010).”
Mitochondria: In Sickness and in Health (2012, neutral): “Leading Edge”
Early evolution of the Eukaryota (2015, background): “…the radiation of large armoured eukaryotes (e.g. Hamm et al. 2003), just as it is for the associated Mesozoic marine revolution (Vermeij 1977), the Cambrian explosion and, potentially, the c. 750 Ma spike in armoured microfossils and sterane abundance (Pawlowska et al. 2013; Lenton et al. 2014).”
Hypoxia-Inducible Factors in Physiology and Medicine (2012, background): “Energy produced by mitochondrial respiration is sufficient to power the development and maintenance of multicellular organisms, which could not be sustained by energy produced by glycolysis alone (Lane and Martin, 2010).”
The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms (2011, background): “However, the number of genes has increased only about fourfol”
Consistent temperature dependence of respiration across ecosystems contrasting in thermal history (2012, background): “This suggests that E might represent a relatively fixed property across species and environments, reflecting the conservation of a core biochemistry of oxygenic metabolism among the main domains of life (Lane & Martin, 2010).”
MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads (2023, neutral): “…from an ancient symbiosis between the last common ancestor of all eukaryotes and an alphaproteobacterial cell, and while many genes that were on the ancestral bacterial genome have been transferred to the nuclear genome [10], the mitochondrion generally retains a reduced, circular genome [11].”
The human mitochondrial transcriptome (2011, positive): “…ancestor, the mitochondrial genome has been streamlined into a small, high-copy, bioenergetically specialized genetic system that allows individual mitochondria to respond by gene expression to changes in membrane potential and maintain oxidative phosphorylation (Lane and Martin, 2010).”