Origins of highly mosaic mycobacteriophage genomes.

By M. Pedulla, M. E. Ford, Jennifer M. Houtz, Tharun Karthikeyan, Curtis Wadsworth, John A. Lewis, D. Jacobs-Sera, Jacob Falbo, J. Gross, Nicholas R. Pannunzio and 10 more. Cell, 2003

678 citations recorded by the source corpus.

Subfields: Ecology, Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/12aefa3d8459fa4d7fd78ebd98129c4e59400130

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Citations in the corpus

Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity (2015, neutral): “The genomes are mosaic whereby individual phages are constructed as assemblages of modules, many of which are single genes (Pedulla et al., 2003).”
Genomic analysis of bacteriophage ε34 of Salmonella enterica serovar Anatum (15+) (2008, neutral): “Background Recent studies of tailed-phages have shown their enormous numbers and wide overall diversity [1-3], but relatively few studies have had as a long-range goal an attempt to analyze the range of diversity in tailed-phages that infect a particular bacterial species or cluster of species (see,”
Phamerator: a bioinformatic tool for comparative bacteriophage genomics (2011, background): “Such comparisons reveal that individual phage genomes are typically constructed from multiple modules - often corresponding to single genes - each of which has a distinctly different phylogeny [10].”
Dark Matter of the Biosphere: the Amazing World of Bacteriophage Diversity (2015, background): “Bacteriophages are the dark matter of the biological world (1); a vastness of ill-defined genetic variation whose impacts we ob-”
Metagenomic Analyses of an Uncultured Viral Community from Human Feces (2003, background): “Similarly, culture-based studies of phage genomes have found that much, if not most, of phage diversity is unsampled (27, 29).”
The Sorcerer II Global Ocean Sampling Expedition: Expanding the Universe of Protein Families (2007, result): “If a sizable portion of the novel families in the GOS data are in fact of viral origin, it suggests that we are far from fully exploring the molecular diversity of viruses, a conclusion echoed in previous studies of viral metagenomes [53,57, 58 ].”
Mobile genetic elements: the agents of open source evolution (2005, background): “Phages are the most abundant (∼10 30 tailed phage particles) and the most rapidly replicating (10 25 infections every second) life forms on earth and their genetic diversity is enormou”