Mobile genetic elements: the agents of open source evolution

By L. Frost, Raphaël Leplae, A. Summers, Ariane Toussaint. Nature Reviews Microbiology, 2005

1,785 citations recorded by the source corpus.

Subfields: Ecology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/635db6deb152834ba9f288b9cefc4a857dce4895

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Citations in the corpus

Genomic islands: tools of bacterial horizontal gene transfer and evolution (2008, background): “In addition, it has become clear that mobile elements form by a combination of functional modules, which makes it more difficult to categorize them (Toussaint & Merlin, 2002; Frost et al., 2005; Leplae et al., 2006).”
PHROG: families of prokaryotic virus proteins clustered using remote homology (2021, background): “Thus, 5% of the proteins can be considered as real ORFans, a value much lower than what is usually described.”
Ecology of viruses in soils: Past, present and future perspectives (2008, background): “2005 ), the greatest genetic reservoirs on Earth ( Frost et al . 2005 ; Paul and Sullivan 2005 ; Weinbauer and Rassoulzadegan 2004 ), and mediators of horizontal gene transfer ( Breitbart et al .”
ACLAME: A CLAssification of Mobile genetic Elements, update 2010 (2009, background): “Phages, plasmids, transposons and insertion sequences (IS) are members of the MGE population [generally called the mobilome (1)], a central player in mobilizing and reorganizing genes, be it within a given genome (intracellular mobility) or between bacterial cells (inter-cellular mobility).”
PathogenFinder - Distinguishing Friend from Foe Using Bacterial Whole Genome Sequence Data (2013, background): “Unluckily this approach is not always reliable, partly because of HGT, which causes these features to be exchanged among pathogenic and innocuous strains of the same [15][16] or different species, an exchange which has been proved by the high amount of these features found in genomic islands [17].”
Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world (2008, background): “All sequenced prokaryotic genomes contain traces of integration of multiple plasmids and phages (216).”
The Hologenome Concept: Human, Animal and Plant Microbiota (2014, background): “HGT is mediated by transposons, plasmids, genomic islands, and viruses, including bacteriophages, which can be either on bacterial chromosomes or on plasmids (Frost et al. 2005).”
Next-Generation Sequencing — An Overview of the History, Tools, and “Omic” Applications (2016, background): “PMID: 18076328 [247] Frost LS, Leplae R, Summers AO, Toussaint A: Mobile genetic elements: The agents of open source evolution.”
Mobility of Plasmids (2010, background): “First, it allows homologous recombination between closely related strains or species in a process resembling eukaryotic sex (55, 142).”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “…lysis, as well as that mediated by plasmids in the aquatic environment and in the intestines of fish and terrestrial animals (Stewart and Sinigalliano, 1990; Beaber et al., 2004; Frost et al., 2005; Aarestrup et al., 2008; Allen et al., 2011; Domingues et al., 2012; Looft et al., 2012).”
DRAM for distilling microbial metabolism to automate the curation of microbiome function (2020, background): “The ‘transposon’ flag (T) is given when the gene is on a contig that contains a transposon, highlighting to the user that this contig requires further inspection as it may be a non-viral mobile genetic element (64,65).”
Rethinking Protein Drug Design with Highly Accurate Structure Prediction of Anti-CRISPR Proteins (2021, background): “In future, utilizing the ability of small proteins to engage in indirect interference through enzymatic activities is to be explored against disease-causing proteins (such as in cancer) and disease-causing organisms (such as drug-resistant bacteria) [36].”