Metagenomic Analyses of an Uncultured Viral Community from Human Feces

By Mya Breitbart, I. Hewson, B. Felts, J. Mahaffy, J. Nulton, Peter Salamon, Forest Rohwer. Journal of Bacteriology, 2003

767 citations recorded by the source corpus.

Subfields: Ecology, Infectious Diseases, Plant Science

View Paper: https://www.semanticscholar.org/paper/ca85b6461714edc95e455f79efd2265f40ced451

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Citations in the corpus

Bacteriophages of the Human Gut: The "Known Unknown" of the Microbiome. (2019, background): “While >80% of viral sequences did notmatch against closed-reference databases, most of the classifiable metagenomic reads aligned to Siphoviridae phage genomes (Breitbart et al., 2003; Reyes et al., 2010).”
Disease-specific Alterations in the Enteric Virome in Inflammatory Bowel Disease (2015, background): “Disparate ratios of Caudovirales and Microviridae were also observed in patients from Los Angeles.”
The Messinian Salinity Crisis from mega-deposits to microbiology – A consensus report (2008, methodology): “Although RNA and single-stranded DNA (ssDNA) phages were thought to be rare in the water column (Breitbart et al., 2003), recently a significant occurrence of ssDNA phages has been reported for marine systems in Sargasso Sea water samples (Angly et al.”
Ecological and evolutionary forces shaping microbial diversity in the human intestine. (2006, unknown): “The alternative strategy, exclusive niche specialization, can result in decreased ability to diversify further (Buckling et al., 2003) and risk to the host that a keystone species is irreplaceably lost in a selective sweep (Cohan, 2002) from, for example, attack by bacteriophages that are abundant i”
Metagenomics: genomic analysis of microbial communities. (2004, background): “Feces LASLa 532 ∼37,000 Random viral (15) clone sequencing”
Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease (2017, background): “(bacteriophage DNA that is integrated into a bacterial genome) (12-16).”
Here a virus, there a virus, everywhere the same virus? (2005, background): “To assess total dsDNA viral diversity, Breitbart et al. partially sequenced shotgun libraries from uncultured viral communities isolated from seawater [35], marine sediment [36] and human fecal matter [ 37 ].”
The Sorcerer II Global Ocean Sampling Expedition: Expanding the Universe of Protein Families (2007, background): “The extraordinary diversity of viruses in a variety of environmental settings is only now beginning to be understood [57,119–121].”
Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity (2012, background): “INTRODUCTION Commensal microbial communities colonize barrier surfaces of the skin, vaginal, upper respiratory, and gastrointestinal tracts of mammals and consist of bacteria, fungi, protozoa, and viruses (Breitbart et al., 2003; Ley et al., 2006a; Scupham et al., 2006).”
Diversity of the human gastrointestinal tract microbiota revisited. (2007, background): “Recent reports indicated that viruses represent another important constituent, as more then 1200 viral genotypes were identified in human faeces with a density of up to 10(9) virions per g of dry material (Breitbart et al., 2003; Zhang et al., 2006).”