Regulation of receptor trafficking by GRKs and arrestins.

By C. C. Moore, S. Milano, J. Benovic. Annual Review of Physiology, 2007

705 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

β-arrestin-mediated receptor trafficking and signal transduction (2011, background): “Studies that characterized a direct interaction between β-arrestin1 and clathrin have shed light on the mechanisms by which β-arrestins promote 7TMR endocytosis [15].”
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. (2008, background): “However, arrestin binding is now recognized to be an important mediator of receptor internalization through interactions with clathrin and AP-2 (53).”
Arf Family G Proteins and their regulators: roles in membrane transport, development and disease (2011, background): “GIT1 and its substrate ARF6 affect ligand-stimulated endocytosis of several GPCRs through either clathrin-dependent or clathrin-independent endocytic pathways 119 .”
Endocytosis and signalling: intertwining molecular networks (2009, neutral): “This adaptor function is promoted by the ligand-induced activation of receptors and by GPCR kinase-induced phosphorylation of cytoplasmic serine and threonine residues in the recepto”