Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil

By G. Beauchamp, R. Keast, D. Morel, Jianming Lin, J. Pika, Qiang Han, Chi-Ho Lee, Amos B. Smith, P. Breslin. Nature, 2005

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The Immunomodulatory and Anti-Inflammatory Role of Polyphenols (2018, background): “Oleocanthal— ike ibuprofen—i hibits COX-1 and COX-2 activities in a dosee e dent man er [120].”
Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms (2018, neutral): “Furthermore, it has been shown that 50 g of newly pressed extravirgin olive oil contains up to 9 mg of olechantal, a phytochemical with ibuprofen-like COX-inhibitory activity (61).”
Responses to extra virgin olive oils in consumers with varying commitment to oils (2012, background): “The high content of polyunsaturated fatty acids and phenolic compounds are considered to be health benefits of olive oil (Beauchamp et al., 2005; Tripoli et al., 2004).”
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity – A Comprehensive Review (2016, positive): “For instance, extra virgin olive oil contains oleocanthal, a phenolic that binds cyclooxygenase (COX) 1 and 2 receptors (causing a characteristic burning throat sensation, similar to that induced by chewing no coated aspirin) and exhibits anti-inflammatory properties.(30,251,252) In the PREDIMED ran”