JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

By Diego Pasini, P. Cloos, J. Walfridsson, L. Olsson, John-Paul Bukowski, J. Johansen, M. Bak, N. Tommerup, Juri Rappsilber, K. Helin. Nature, 2010

613 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0ff121b56ef3da723bffc770b5e12cddaa797b74

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Citations in the corpus

Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put (2013, positive): “Thus, PCL3 is functionally more robust than PCL2 in ESCs, and the two orthologs are not simply redundant.”
Control of Embryonic Stem Cell State (2011, background): “…during differentiation (Azuara et al., 2006; Bernstein et al., 2006; Boyer et al., 2006; Bracken et al., 2006; Endoh et al., 2008; Landeira et al., 2010; Lee et al., 2006; Li et al., 2010; Pan et al., 2007; Pasini et al., 2010; Peng et al., 2009; Shen et al., 2009; van der Stoop et al., 2008).”
Genome-wide identification of Polycomb-associated RNAs by RIP-seq (2010, background): “, 2010) and Jarid2 may facilitate binding (Li et al., 2010; Pasini et al., 2010; Peng et al., 2009; Shen et al., 2009).”
Transcriptional regulation by Polycomb group proteins (2013, background): “; and from the Novo Nordisk Foundation, the Danish Cancer Society and the Danish Council for Strategic Research (12-110503) to K.”
Genome Regulation by Polycomb and Trithorax: 70 Years and Counting. (2017, positive): “PRC2 compositional diversity is achieved through association with non-stoichiometric subunits (hereafter called accessory proteins) that can modulate its enzymatic activities or chromatin target sites (Ciferri et al., 2012; Li et al., 2010; Pasini et al., 2010; Shen et al., 2009).”
A double take on bivalent promoters. (2013, background): “Genomic binding sites of Jarid2, an interactor of PRC2, exhibit significant overlap with PRC2 target sites in ES cells (Peng et al. 2009; Shen et al. 2009; Landeira et al. 2010; Li et al. 2010; Pasini et al. 2010).”
Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact (2012, positive): “recruitment to target genes (Li et al., 2010; Pasini et al., 2010; Peng et al., 2009; Shen et al., 2009).”
ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases (2016, background): “The upregulation of many PRC target genes leads to global epigenetic changes [209–211].”