Integrons: agents of bacterial evolution

By D. Mazel. Nature Reviews Microbiology, 2006

1,085 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/0e3b7dffc0e9f309b19b64dcdd77dbf705b6c1d0

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Citations in the corpus

Antimicrobial Resistance in Bacteria: Mechanisms, Evolution, and Persistence (2019, neutral): “2007; Mazel 2006).”
Multidrug Resistance in Bacteria (2009, background): “It is unclear how the modern integrons evolved, but there is a rather similar mechanism that builds the assembly of many genes in Vibrio cholerae (34).”
Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens. (2011, background): “Integrons have been present in the Proteobacteria for a very long time (Mazel, 2006; Boucher et al., 2007).”
The population genetics of commensal Escherichia coli (2010, background): “Integrons are molecular structures that are of great importance for the spread and expression of antibiotic resistance gene”
ISsaga is an ensemble of web-based methods for high throughput identification and semi-automatic annotation of insertion sequences in prokaryotic genomes (2011, background): “It is hoped that ISsaga will be extended to other mobile genetic elements such as transposons, integrative conjugative elements (ICEs) [18] and integrons [19].”
Acquired Antibiotic Resistance Genes: An Overview (2011, background): “, an attI recombination site and a 59-base element (attC site) where attI is the target site for cassette integration and a promoter (Hall and Stokes, 1993; Hall and Collis, 1995; Rechia and Hall, 1997; Mazel, 2006).”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “…can be mobilized by transposons and plasmids to generate new permutations of resistance genes (Rowe-Magnus and Mazel, 1999; L’Abee-Lund and Sørum, 2001; Mazel, 2006; Boucher et al., 2007; Jacobs and Chenia, 2007; Gillings et al., 2008; Laroche et al., 2009; Xia et al., 2010; Stalder et al., 2012).”
Horizontal Gene Exchange in Environmental Microbiota (2011, methodology): “The main genetic engineering tool used by bacteria to collect antibiotic resistance genes is integrons, the genetic platform that is involved in the acquisition and functional expression of exogenous gene cassettes (Mazel, 2006).”
Antibiotic resistance plasmids in wastewater treatment plants and their possible dissemination into the environment (2010, background): “Retrospective studies highlighted the role of integrons and their gene cassettes in genome evolution within bacterial populations (Mazel, 2006; Boucher et al., 2007; Gillings et al., 2008) and perhaps their association with conjugative transfer plasmids and transposons could play a major role in rap”
Bacterial insertion sequences: their genomic impact and diversity (2014, background): “They often carry integron recombination platforms enabling them to incorporate additional resistance genes by recruiting integron cassettes (Mazel, 2006).”
Integrons: Past, Present, and Future (2014, background): “The diversity of cassettes with other inferred functions is impressive, covering DNA modification, functions related to phage, polysaccharide biosynthesis, amino acid synthesis, transporters, and efflux systems, to name a few (1, 17, 21, 112, 113).”